User profiles for G. Ferwerda

Gerben Ferwerda

MD PhD
Verified email at radboudumc.nl
Cited by 9064

[HTML][HTML] Fc-mediated antibody effector functions during respiratory syncytial virus infection and disease

EA Van Erp, W Luytjes, G Ferwerda… - Frontiers in …, 2019 - frontiersin.org
… It was shown that Fab fragments of the 1812A2B anti-RSV G antibody and F(ab') 2 fragments
of the 131-2G anti-RSV G antibody do not reduce viral load, whereas the corresponding …

How uterine microbiota might be responsible for a receptive, fertile endometrium

M Benner, G Ferwerda, I Joosten… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Fertility depends on a receptive state of the endometrium, influenced by
hormonal and anatomical adaptations, as well as the immune system. Local and systemic …

[HTML][HTML] Human dectin-1 deficiency and mucocutaneous fungal infections

B Ferwerda, G Ferwerda, TS Plantinga… - … England Journal of …, 2009 - Mass Medical Soc
<p id="p001">Mucocutaneous fungal infections are typically found in patients who have no
known immune defects. We describe a family in which four women who were affected by …

Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages

…, FL van de Veerdonk, G Ferwerda… - Blood, The Journal …, 2009 - ashpublications.org
The processing of pro-interleukin-1β depends on activation of caspase-1. Controversy has
arisen whether Toll-like receptor (TLR) ligands alone can activate caspase-1 for release of …

Recognition of fungal pathogens by toll-like receptors

MG Netea, G Ferwerda… - Current …, 2006 - ingentaconnect.com
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition receptors.
Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, either alone …

[HTML][HTML] Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

…, G Ferwerda, RP Hobson, G Bertram… - The Journal of …, 2006 - Am Soc Clin Investig
The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer
layer of proteins glycosylated with N-or O-linked mannosyl residues and an inner skeletal …

Syk kinase is required for collaborative cytokine production induced through Dectin‐1 and Toll‐like receptors

KM Dennehy, G Ferwerda… - European journal of …, 2008 - Wiley Online Library
Recognition of microbial components by germ‐line encoded pattern recognition receptors (PRR)
initiates immune responses to infectious agents. We and others have proposed that …

[HTML][HTML] NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

G Ferwerda, SE Girardin, BJ Kullberg… - PLoS …, 2005 - journals.plos.org
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide.
Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both …

Dectin‐1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

G Ferwerda, F Meyer‐Wentrup, BJ Kullberg… - Cellular …, 2008 - Wiley Online Library
The β‐glucan receptor dectin‐1 and Toll‐like receptors TLR2 and TLR4 are the main receptors
for recognition of Candida albicans by the innate immune system. It has been reported …

Immune Recognition of Candida albicans β-glucan by Dectin-1

…, MG Netea, CA Munro, G Ferwerda… - The Journal of …, 2007 - academic.oup.com
β(1,3)-glucans represent 40% of the cell wall of the yeast Candida albicans. The dectin-1
lectin-like receptor has shown to recognize fungal β(1,3)-glucans and induce innate immune …