Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …

Objective. To update the 1997 OMERACT-OARSI (Outcome Measures in Rheumatology-Osteoarthritis
Research Society International) core domain set for clinical trials in hip and/or …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage.
The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD …

A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with …

We have performed genetic linkage analysis in 13 large multiply affected families, to test the
hypothesis that there is extensive heterogeneity of linkage for genetic subtypes of …

Genome sequence analysis has enabled significant advancements in medical and scientific
areas such as personalized medicine, outbreak tracing, and the understanding of evolution. …

A lectin isolated from the roots of the legume, Dolichos biflorus, binds to Nod factors produced
by rhizobial strains that nodulate this plant and has a deduced amino acid sequence with …

Alcohol dependence (AD) is a common, chronic, relapsing disorder. Compelling epidemiological
evidence indicates that >50% of the risk for becoming alcoholic stems from genetic …

… M-channels are characteristically inhibited by the activity of hormones and transmitters on
G-protein coupled receptors. Modulation of ligand-gated ion channels is critical to producing …