Nucleus centering in mouse oocytes results from a gradient of actin-positive vesicle activity
and is essential for developmental success. Here, we analyze 3D model simulations to …

Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of
actin-based structures. Although the biochemical composition and filament organization of …

Actomyosin contractility plays a central role in a wide range of cellular processes, including
the establishment of cell polarity, cell migration, tissue integrity, and morphogenesis during …

Motivation Due to the complexity and heterogeneity of multicellular biological systems,
mathematical models that take into account cell signalling, cell population behaviour and the …

… When the S1 peak is the main concern, e.g. for reservoir units studies, an alternative built-in
method, the “Reservoir” method, is available. This method is usually performed on cutting or …

… Using g-tubulin as a marker for centrosome, we investigated the polarity of cell populations
destined for different cell fates. The centrosome in epiblast cells was localized close to the …

Successive cell divisions during embryonic cleavage create increasingly smaller cells, so
intracellular structures must adapt accordingly. Mitotic spindle size correlates with cell size, but …

… The supernatant was layered on top of a double gradient formed by Histopaque-1119 and
-1077 (Sigma) following the manufacturer's recommendations and centrifuged at 700 × g for …

… was “pinned” by a spring of stiffness k g acting between the microtubule plus end and the
point … is strongly impaired, and the impediment depends on k g . It is interesting to note that we …

Primary cilia are sensory organelles located at the cell surface. Their assembly is primed by
centrosome migration to the apical surface, yet surprisingly little is known about this initiating …