User profiles for G. Sherlock

Gavin Sherlock

Professor of Genetics, Stanford University
Verified email at stanford.edu
Cited by 114045

Analysis of large-scale gene expression data

G Sherlock - Current opinion in immunology, 2000 - Elsevier
The advent of cDNA and oligonucleotide microarray technologies has led to a paradigm
shift in biological investigation, such that the bottleneck in research is shifting from data …

Comparison of the complete protein sets of worm and yeast: orthology and divergence

SA Chervitz, L Aravind, G Sherlock, CA Ball, EV Koonin… - Science, 1998 - science.org
Comparative analysis of predicted protein sequences encoded by the genomes of
Caenorhabditis elegans and Saccharomyces cerevisiae suggests that most of the core biological …

The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources

…, SR Miyasato, M Simison, G Sherlock… - Nucleic acids …, 2012 - academic.oup.com
The Aspergillus Genome Database (AspGD; http://www.aspgd.org ) is a freely available,
web-based resource for researchers studying fungi of the genus Aspergillus, which includes …

Gene ontology: tool for the unification of biology

…, JE Richardson, M Ringwald, GM Rubin, G Sherlock - Nature …, 2000 - nature.com
Genomic sequencing has made it clear that a large fraction of the genes specifying the core
biological functions are shared by all eukaryotes. Knowledge of the biological role of such …

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

…, J Hudson Jr, L Lu, DB Lewis, R Tibshirani, G Sherlock… - Nature, 2000 - nature.com
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's lymphoma,
is clinically heterogeneous: 40% of patients respond well to current therapy and have …

Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization

PT Spellman, G Sherlock, MQ Zhang… - Molecular biology of …, 1998 - Am Soc Cell Biol
We sought to create a comprehensive catalog of yeast genes whose transcript levels vary
periodically within the cell cycle. To this end, we used DNA microarrays and samples from …

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

A Brazma, P Hingamp, J Quackenbush, G Sherlock… - Nature …, 2001 - nature.com
Microarray analysis has become a widely used tool for the generation of gene expression data
on a genomic scale. Although many significant results have been derived from microarray …

Missing value estimation methods for DNA microarrays

O Troyanskaya, M Cantor, G Sherlock, P Brown… - …, 2001 - academic.oup.com
Motivation: Gene expression microarray experiments can generate data sets with multiple
missing expression values. Unfortunately, many algorithms for gene expression analysis …

GO:: TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of …

…, H Jin, D Botstein, JM Cherry, G Sherlock - …, 2004 - academic.oup.com
GO::TermFinder comprises a set of object-oriented Perl modules for accessing Gene Ontology
(GO) information and evaluating and visualizing the collective annotation of a list of genes …

Identification of genes periodically expressed in the human cell cycle and their expression in tumors

ML Whitfield, G Sherlock, AJ Saldanha… - Molecular biology of …, 2002 - Am Soc Cell Biol
The genome-wide program of gene expression during the cell division cycle in a human
cancer cell line (HeLa) was characterized using cDNA microarrays. Transcripts of >850 genes …