User profiles for G. de Guglielmo

Giordano de Guglielmo

University of California, San Diego
Verified email at ucsd.edu
Cited by 1956

Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond

…, N Cannella, S Braconi, M Kallupi, G de Guglielmo… - Alcohol, 2009 - Elsevier
This article summarizes the proceedings of a symposium held at the conference on “Alcoholism
and Stress: A Framework for Future Treatment Strategies” in Volterra, Italy, May 6–9, …

The cocaine and oxycodone biobanks, two repositories from genetically diverse and behaviorally characterized rats for the study of addiction

LLG Carrette, G de Guglielmo, M Kallupi, L Maturin… - eneuro, 2021 - eneuro.org
… Tubing is inserted into the vein following a needle puncture (22 G) and secured with a suture.
The guide cannula is punctured through a small incision on the back. The outer part of the …

[HTML][HTML] Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition

JL Zhou, G de Guglielmo, AJ Ho, M Kallupi… - Nature …, 2023 - nature.com
The amygdala processes positive and negative valence and contributes to addiction, but the
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas …

[HTML][HTML] Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats

G de Guglielmo, M Kallupi, MB Pomrenze… - Nature …, 2019 - nature.com
… f, g Optogenetic inhibition of CeA CRF neurons did not alter the (f) total distance traveled (t
8 … g–j Representative pictures of the different experimental conditions that are depicted in e. …

[HTML][HTML] A transgenic rat for investigating the anatomy and function of corticotrophin releasing factor circuits

…, J Dadgar, V Kharazia, G De Guglielmo… - Frontiers in …, 2015 - frontiersin.org
… in adolescent rats weighing 200–220 g. Coordinates for the BNST were AP +0.00, ML ±3.5,
DV −6.8 with a 16 angle in adolescent rats weighing 200–220 g. After injection, we waited 10 …

Recruitment of a neuronal ensemble in the central nucleus of the amygdala is required for alcohol dependence

G de Guglielmo, E Crawford, S Kim… - Journal of …, 2016 - Soc Neuroscience
Abstinence from alcohol is associated with the recruitment of neurons in the central nucleus
of the amygdala (CeA) in nondependent rats that binge drink alcohol and in alcohol-…

Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors

R Ciccocioppo, G de Guglielmo… - Journal of …, 2014 - Soc Neuroscience
Corticotropin releasing factor (CRF) is the primary mediator of stress responses, and
nociceptin/orphanin FQ (N/OFQ) plays an important role in the modulation of these stress responses…

Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents

…, FP Varodayan, JM Truitt, G de Guglielmo… - Journal of …, 2017 - Soc Neuroscience
Toll-like receptor 4 (TLR4) is a critical component of innate immune signaling and has been
implicated in alcohol responses in preclinical and clinical models. Members of the …

Activation of PPAR γ by Pioglitazone Potentiates the Effects of Naltrexone on Alcohol Drinking and Relapse in ms P Rats

S Stopponi, G de Guglielmo, L Somaini… - Alcoholism: Clinical …, 2013 - Wiley Online Library
… Giordano de Guglielmo … At 24 hours, water consumption was between 1.3 and 3 g/kg
in the vehicle-treated groups and was not affected by drug treatments (data not shown). …

Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking

…, FC Cruz, LF Vendruscolo, G de Guglielmo… - Journal of …, 2015 - Soc Neuroscience
… Adult male Wistar rats (Charles River), weighing 225–275 g at the beginning of the
experiments, were housed in groups of two to three per cage in a temperature-controlled (22C) …