User profiles for G. de Guglielmo
Giordano de GuglielmoUniversity of California, San Diego Verified email at ucsd.edu Cited by 1956 |
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond
…, N Cannella, S Braconi, M Kallupi, G de Guglielmo… - Alcohol, 2009 - Elsevier
This article summarizes the proceedings of a symposium held at the conference on “Alcoholism
and Stress: A Framework for Future Treatment Strategies” in Volterra, Italy, May 6–9, …
and Stress: A Framework for Future Treatment Strategies” in Volterra, Italy, May 6–9, …
The cocaine and oxycodone biobanks, two repositories from genetically diverse and behaviorally characterized rats for the study of addiction
… Tubing is inserted into the vein following a needle puncture (22 G) and secured with a suture.
The guide cannula is punctured through a small incision on the back. The outer part of the …
The guide cannula is punctured through a small incision on the back. The outer part of the …
[HTML][HTML] Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition
The amygdala processes positive and negative valence and contributes to addiction, but the
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas …
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas …
[HTML][HTML] Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats
G de Guglielmo, M Kallupi, MB Pomrenze… - Nature …, 2019 - nature.com
… f, g Optogenetic inhibition of CeA CRF neurons did not alter the (f) total distance traveled (t
8 … g–j Representative pictures of the different experimental conditions that are depicted in e. …
8 … g–j Representative pictures of the different experimental conditions that are depicted in e. …
[HTML][HTML] A transgenic rat for investigating the anatomy and function of corticotrophin releasing factor circuits
…, J Dadgar, V Kharazia, G De Guglielmo… - Frontiers in …, 2015 - frontiersin.org
… in adolescent rats weighing 200–220 g. Coordinates for the BNST were AP +0.00, ML ±3.5,
DV −6.8 with a 16 angle in adolescent rats weighing 200–220 g. After injection, we waited 10 …
DV −6.8 with a 16 angle in adolescent rats weighing 200–220 g. After injection, we waited 10 …
Recruitment of a neuronal ensemble in the central nucleus of the amygdala is required for alcohol dependence
G de Guglielmo, E Crawford, S Kim… - Journal of …, 2016 - Soc Neuroscience
Abstinence from alcohol is associated with the recruitment of neurons in the central nucleus
of the amygdala (CeA) in nondependent rats that binge drink alcohol and in alcohol-…
of the amygdala (CeA) in nondependent rats that binge drink alcohol and in alcohol-…
Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors
R Ciccocioppo, G de Guglielmo… - Journal of …, 2014 - Soc Neuroscience
Corticotropin releasing factor (CRF) is the primary mediator of stress responses, and
nociceptin/orphanin FQ (N/OFQ) plays an important role in the modulation of these stress responses…
nociceptin/orphanin FQ (N/OFQ) plays an important role in the modulation of these stress responses…
Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents
…, FP Varodayan, JM Truitt, G de Guglielmo… - Journal of …, 2017 - Soc Neuroscience
Toll-like receptor 4 (TLR4) is a critical component of innate immune signaling and has been
implicated in alcohol responses in preclinical and clinical models. Members of the …
implicated in alcohol responses in preclinical and clinical models. Members of the …
Activation of PPAR γ by Pioglitazone Potentiates the Effects of Naltrexone on Alcohol Drinking and Relapse in ms P Rats
S Stopponi, G de Guglielmo, L Somaini… - Alcoholism: Clinical …, 2013 - Wiley Online Library
… Giordano de Guglielmo … At 24 hours, water consumption was between 1.3 and 3 g/kg
in the vehicle-treated groups and was not affected by drug treatments (data not shown). …
in the vehicle-treated groups and was not affected by drug treatments (data not shown). …
Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking
… Adult male Wistar rats (Charles River), weighing 225–275 g at the beginning of the
experiments, were housed in groups of two to three per cage in a temperature-controlled (22C) …
experiments, were housed in groups of two to three per cage in a temperature-controlled (22C) …