[HTML][HTML] Curcumin potentiates the effect of chemotherapy against acute lymphoblastic leukemia cells via downregulation of NF‑κB

HJ Pimentel-Gutiérrez… - Oncology …, 2016 - spandidos-publications.com
Acute lymphoblastic leukemia (ALL) accounts for 30% of all pediatric cancers. Currently
available treatments exhibit toxicity and certain patients may develop resistance. Thus, less toxic …

Aneuploidy in children with relapsed B‐cell precursor acute lymphoblastic leukaemia: clinical importance of detecting a hypodiploid origin of relapse

…, MJ Pogodzinski, HJ Pimentel‐Gutiérrez… - British journal of …, 2019 - Wiley Online Library
Aneuploidy is common in paediatric B‐cell precursor acute lymphoblastic leukaemia (ALL).
Specific subgroups, such as high hyperdiploidy (>50 chromosomes or DNA Index ≥1·16) …

[HTML][HTML] Expression profile of NF-κB regulated genes in sporadic colorectal cancer patients

…, HJ Pimentel‑Gutiérrez… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is the fourth leading worldwide cause of cancer‑associated mortalities.
Nuclear factor‑κB (NF‑κB) is a transcriptional regulator of multiple genes associated with …

Aneuploidy identification in pre-B acute lymphoblastic leukemia patients at diagnosis by Multiplex Ligation-dependent Probe Amplification (MLPA)

…, A Márquez-Mora, HJ Pimentel-Gutiérrez… - Leukemia Research, 2017 - Elsevier
Three-quarters of the patients with acute lymphoblastic leukemia (ALL), show numerical or
structural chromosomal alterations, which are important factors in leukemogenesis. The use …

Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation

J Lázaro-Navarro, HJ Pimentel-Gutiérrez… - Blood …, 2021 - ashpublications.org
The treatment resistance and high morbidity associated with conventional chemotherapeutic
treatments warrant new therapeutic approaches for B-cell precursor acute lymphoblastic …

IKZF1 gene deletion in pediatric patients diagnosed with acute lymphoblastic leukemia in Mexico

MF Ayón-Pérez, HJ Pimentel-Gutiérrez… - … and Genome Research, 2019 - karger.com
… Briefly, MF Ayón-Pérez, PhD, performed the qPCR and MLPA analysis; HJ Pimentel-Gutiérrez,
PhD, carried out the analyses of results and clinical data. The student, VM Pérez-Peraza, …

[HTML][HTML] Pediatric donor cell leukemia after allogeneic hematopoietic stem cell transplantation in AML patient from related donor

L Bobadilla-Morales, HJ Pimentel-Gutiérrez… - Molecular …, 2015 - Springer
Here we present a male patient with acute myeloid leukemia (AML) initially diagnosed as
M5 and with karyotype 46,XY. After induction therapy, he underwent a HLA-matched …

Hosting multiple simultaneous applications over an easy to administrate, scalable, extensible platform integrating diverse computational resources

HJ Pimentel, SH Courellis… - 2009 WRI World …, 2009 - ieeexplore.ieee.org
Many Scientific Groups could obtain significant computational power if they integrated the
diverse computational resources and the computational clusters they own. In this paper, we …

Hydrogen bonding

GC Pimentel, AL McClellan - Annual Review of Physical …, 1971 - annualreviews.org
… Nibler & Pimentel (77). Their infrared studies of cesium … (Note that the work of Nibler &
Pimentel leaves uncertain the … With this discriminating test in mind Pimentel and co-workers (…

Gravitational perturbation of the hydrogen spectrum

L Parker, LO Pimentel - Physical Review D, 1982 - APS
The perturbations of the energy levels of a freely falling one-electron atom in an arbitrary
external gravitational field are considered. The energy-level shifts are calculated to first order in …