Complex motivated behavioral processes, such as those that can go awry following substance
abuse and other neuropsychiatric disorders, are mediated by a distributive network of …

Forming and breaking associations between emotionally salient environmental stimuli and
rewarding or aversive outcomes is an essential component of learned adaptive behavior. …

Several neuropsychiatric conditions, such as addiction and schizophrenia, may arise in part
from dysregulated activity of ventral tegmental area dopaminergic (TH VTA) neurons, as well …

Objective: Antidopaminergic drugs bind to hERG1 potassium channels encoded by the gene
KCNH2, which accounts for the side effect of QT interval prolongation. KCNH2 has also …

Very-long-chain polyunsaturated fatty acids (VLCPUFAs; C24-38) constitute a unique class
of PUFA that have important biological roles, but the lack of a suitable dietary source has …

Neurexins are presynaptic neuronal adhesion molecules that interact with postsynaptic
neuroligins to form an inter-synaptic complex required for synaptic specification and efficient …

… 20, 200, to 400 nM for 3 h followed by 250 µM H 2 O 2 for an additional 24 h. The induction
of ROS triggered by H 2 O 2 was inhibited in cells pre-treated for 3 h with NAC, a major free …

… fMRI scans were performed 2 h after tolcapone administration on … –2 h after oral administration
and maximum inhibition of COMT activity in red blood cells is reached between 1 and 4 h …

… cold 10 mM HEPES, pH 9.0, and incubate in the same buffer for 3 h at 4 C without agitation.
… Acyl ceramide (AcylCer) species are detected primarily as [M + HCO2-H] − ions under the …

… VTA glutamatergic neurons, in addition to providing local excitatory drive onto VTA DA
neurons that project to the NAc and cause rewarding behavioral effects (H.-L. Wang et al., 2015), …