A subset of patients with advanced castration-resistant prostate cancer may eventually evolve
into an androgen receptor (AR)–independent phenotype, with a clinical picture associated …

The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert
Panel identified and reviewed the available evidence for the ten most important areas of …

Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …

A primary culture, 734B, was grown from a pleural effusion of a patient with metastatic
mammary carcinoma. This culture continually produced free-floating cells used to initiate serial …

Two sublines of a breast epithelial cell culture, MCF-10, derived from human fibrocystic
mammary tissue exhibit immortality after extended cultivation in low calcium concentrations (0.03…

Background In advanced prostate cancer (APC), successful drug development as well as
advances in imaging and molecular characterisation have resulted in multiple areas where …

The MCF10 series of cell lines was derived from benign breast tissue from a woman with
fibrocystic disease. The MCF10 human breast epithelial model system consists of mortal …

Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but there are still many aspects of management …

Purpose Adjuvant therapy for intermediate-risk and high-risk localized prostate cancer
decreases the number of deaths from this disease. Surrogates for overall survival (OS) could …

PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized multigene …