… barcode mRNA molecule with a random 12-nt unique molecular identifier (UMI). We also
added a 6-nt slicespecific identifier (SSI) to allow multiplexing of samples within a single high-…

… However, such physiological approaches tend to obscure the identity of the neurons under
study. From the point of view of conventional extracellular recording, neurons within a brain …

The function of a neural circuit is determined by the details of its synaptic connections. At
present, the only available method for determining a neural wiring diagram with single synapse …

Heterogeneity is a ubiquitous feature of biological systems. A complete understanding of
such systems requires a method for uniquely identifying and tracking individual components …

… Active-marker systems have an advantage because marker identity can be easily and quickly
recognized. Each marker emits a signal that differs in frequency or pattern. However, these …

… In the kth cycle, a fluorescent tag is introduced, the color of which corresponds to the identity
of the kth base along the rolony’s parent DNA strand. The system is then “paused” in this …

Electrical stimulation of nervous tissue has been extensively used as both a tool in experimental
neuroscience research and as a method for restoring of neural functions in patients …

We analyze the scaling and cost-performance characteristics of current and projected
connectomics approaches, with reference to the potential implications of recent advances in …

The ability to walk may be critically impacted as the result of neurological injury or disease.
While recent advances in brain-machine interfaces (BMIs) have demonstrated the feasibility …

We present a high-voltage, high-precision multi-channel system capable of stimulating
neural activity through bi-phasic pulses of amplitude up to ±50 V while recording very low-voltage …