Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration
DE Wagner, IE Wang, PW Reddien - Science, 2011 - science.org
… S3E), indicating that smedwi-1 + cluster expansion results from division of existing smedwi-1
+ cells (ie, by clonal growth). If some other process, such as dedifferentiation, had produced …
+ cells (ie, by clonal growth). If some other process, such as dedifferentiation, had produced …
Pharmacologic and nonpharmacologic treatment for acute cough associated with the common cold: CHEST Expert Panel Report
MA Malesker, P Callahan-Lyon, B Ireland, RS Irwin… - Chest, 2017 - Elsevier
Background Acute cough associated with the common cold (CACC) causes significant
impairment in quality of life. Effective treatment approaches are needed for CACC. We conducted …
impairment in quality of life. Effective treatment approaches are needed for CACC. We conducted …
[PDF][PDF] MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to aurora kinase inhibition
…, C Heinen, MD Chalishazar, H Cheng, AS Ireland… - Cancer cell, 2017 - cell.com
Loss of the tumor suppressors RB1 and TP53 and MYC amplification are frequent oncogenic
events in small cell lung cancer (SCLC). We show that Myc expression cooperates with …
events in small cell lung cancer (SCLC). We show that Myc expression cooperates with …
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
…, C Feig, C Combs, SP Winter, H Ireland-Zecchini… - Science, 2009 - science.org
Pancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers in part
because it is insensitive to many chemotherapeutic drugs. Studying a mouse model of PDA …
because it is insensitive to many chemotherapeutic drugs. Studying a mouse model of PDA …
Profile-based string kernels for remote homology detection and motif extraction
We introduce novel profile-based string kernels for use with support vector machines (SVMs)
for the problems of protein classification and remote homology detection. These kernels …
for the problems of protein classification and remote homology detection. These kernels …
Distribution and evolution of circular miniproteins in flowering plants
Cyclotides are disulfide-rich miniproteins with the unique structural features of a circular
backbone and knotted arrangement of three conserved disulfide bonds. Cyclotides have been …
backbone and knotted arrangement of three conserved disulfide bonds. Cyclotides have been …
Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans
…, A Balamurugan, G Bauer, JA Ireland… - Blood, The Journal …, 2012 - ashpublications.org
We conducted a gene therapy trial in 10 patients with adenosine deaminase (ADA)–deficient
severe combined immunodeficiency using 2 slightly different retroviral vectors for the …
severe combined immunodeficiency using 2 slightly different retroviral vectors for the …
Effect of airborne contaminants on the wettability of supported graphene and graphite
It is generally accepted that supported graphene is hydrophobic and that its water contact
angle is similar to that of graphite. Here, we show that the water contact angles of freshly …
angle is similar to that of graphite. Here, we show that the water contact angles of freshly …
[PDF][PDF] Radiotherapy as primary treatment for stage IE and IIE nasal natural killer/T-cell lymphoma
…, B Yao, J Jin, WH Wang, YP Liu, YW Song, SL Wang… - J Clin Oncol, 2006 - Citeseer
… The purpose of this study is to analyze the outcome of radiotherapy as the primary
treatment for localized stage IE and IIE diseases. … Two of the patients with stage IV are …
treatment for localized stage IE and IIE diseases. … Two of the patients with stage IV are …
The impacts of climate change on hydrology in Ireland
A study of nine Irish catchments was carried out to quantify the expected impact of climate
change on hydrology in Ireland. Boundary data from the European Centre Hamburg Model …
change on hydrology in Ireland. Boundary data from the European Centre Hamburg Model …