User profiles for I. Agartz

Ingrid Agartz

Verified email at medisin.uio.no
Cited by 51943

[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

…, B Franke, MJ Wright, NG Martin, I Agartz… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …

[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

…, Y Zhang-James, BM Adhikari, I Agartz… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …

Neuroimaging hippocampal subfields in schizophrenia and bipolar disorder: a systematic review and meta-analysis

…, CK Tamnes, E Söderman, I Agartz - Journal of psychiatric …, 2018 - Elsevier
The hippocampus is a complex structure consisting of subregions with specialized
cytoarchitecture and functions. Magnetic resonance imaging (MRI) studies in psychotic disorders …

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

…, Z Li, G Voloudakis, W Zhang, M Adams, I Agartz… - Nature, 2022 - nature.com
Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Common variants conferring risk of schizophrenia

…, C Arango, J Costas, EG Jönsson, L Terenius, I Agartz… - Nature, 2009 - nature.com
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and
their interactions. Research on pathogenesis has traditionally focused on neurotransmitter …

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

…, ME Goddard, JS Witte, D Absher, I Agartz… - Nature …, 2013 - cdr.lib.unc.edu
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …

[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores

…, DA Collier, H Huang, TH Pers, I Agartz… - The american journal of …, 2015 - cell.com
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

[HTML][HTML] Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

…, GD Pearlson, OA Andreassen, I Agartz… - Molecular …, 2016 - nature.com
The profile of brain structural abnormalities in schizophrenia is still not fully understood,
despite decades of research using brain scans. To validate a prospective meta-analysis …

[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

…, ME Talkowski, LA Weiss, AJ Willsey, I Agartz… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

…, Z Wang, KVF Fajarado, MS Maile, S Ripke, I Agartz… - Nature …, 2017 - nature.com
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …