User profiles for J. C. Schwartz

Jae Schwartz

Principal Scientist, ThermoFisher Scientific
Verified email at thermofisher.com
Cited by 6901

International Union of Pharmacology. XIII. Classification of histamine receptors

SJ Hill, CR Ganellin, H Timmerman, JC Schwartz… - Pharmacological …, 1997 - ASPET
The classification of histamine receptors has to date been based on rigorous classical
pharmacological analysis, and as yet, the classification of the three histamine receptors that have …

Histaminergic transmission in the mammalian brain

JC Schwartz, JM Arrang, M Garbarg… - Physiological …, 1991 - journals.physiology.org
The recognition of histamine (HA)[or 2 (4-imidazolyl) ethylamine] as a messenger molecule
in cell-to-cell communication began early in this century. The early history of HA was …

The histamine H3 receptor: from discovery to clinical trials with pitolisant

JC Schwartz - British journal of pharmacology, 2011 - Wiley Online Library
… founded a few years earlier), Jean-Charles Schwartz at Institut National de la Santé et de la
… Ligneau and JC. Schwartz, in preparation); both features oppose H3R inverse agonists to …

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

…, B Giros, MP Martres, ML Bouthenet, JC Schwartz - Nature, 1990 - nature.com
A dopamine receptor has been characterized which differs in its pharmacology and
signalling system from the D 1 or D 2 receptor and represents both an autoreceptor and a …

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

JM Arrang, M Garbarg, JC Schwartz - Nature, 1983 - nature.com
Although histaminergic neurones have not yet been histochemically visualized, there is little
doubt that histamine (HA) has a neurotransmitter role in the invertebrate and mammalian …

Highly potent and selective ligands for histamine H3-receptors

…, H Pollard, M Robba, W Schunack, JC Schwartz - Nature, 1987 - nature.com
New drugs selective for histamine H 3 -receptors can be used to establish that these
receptors are involved in the feedback control ofhistamine synthesis and release, and to …

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

…, H Cadas, S Schinelli, G Cimino, JC Schwartz… - Nature, 1994 - nature.com
ANANDAMIDE (N-arachidonoyl-ethanolamine) was recently identified as a brain arachidonate
derivative that binds to and activates cannabinoid receptors 1–4 , yet the mechanisms …

A two-dimensional quadrupole ion trap mass spectrometer

JC Schwartz, MW Senko, JEP Syka - Journal of the American society for …, 2002 - Springer
The use of a linear or two-dimensional (2-D) quadrupole ion trap as a high performance
mass spectrometer is demonstrated. Mass analysis is performed by ejecting ions out a slot in …

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

…, E Souil, MP Martres, P Sokoloff, B Giros, JC Schwartz - Brain research, 1991 - Elsevier
… 13 Giros, B., Martres, ME, Sokoloff, E and Schwartz, JC, Cloning of the human dopaminergic
… and Schwartz, JC, Effects of dopaminergic transmission interruption on the 0 2 receptor …

Alternative splicing directs the expression of two D2 dopamine receptor isoforms

…, MP Martres, JF Riou, LJ Emorine, JC Schwartz - Nature, 1989 - nature.com
DOPAMINE receptors are classified into D l and D 2 subtypes on the basis of their
pharmacological properties and the intracellular responses they mediate 1 . The cerebral D 2 …