[HTML][HTML] Child and adolescent obesity
The prevalence of child and adolescent obesity has plateaued at high levels in most high-income
countries and is increasing in many low-income and middle-income countries. Obesity …
countries and is increasing in many low-income and middle-income countries. Obesity …
[HTML][HTML] The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis
…, WM Bramer, JC Kiefte-de Jong, JF Felix… - The American journal of …, 2016 - Elsevier
Background: The antioxidant lutein is suggested as being beneficial to cardiometabolic
health because of its protective effect against oxidative stress, but evidence has not …
health because of its protective effect against oxidative stress, but evidence has not …
Effects of choline on health across the life course: a systematic review
…, D Gorman, WM Bramer, JF Felix… - Nutrition …, 2015 - academic.oup.com
… Voortman, PK Bautista, JF Felix, and OH Franco are with the Department of Epidemiology,
Erasmus MC, University Medical Center Rotterdam, the Netherlands. R. Chowdhury and D. …
Erasmus MC, University Medical Center Rotterdam, the Netherlands. R. Chowdhury and D. …
New loci associated with kidney function and chronic kidney disease
…, D Ellinghaus, S Schreiber, YS Aulchenko, JF Felix… - Nature …, 2010 - nature.com
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …
have identified common CKD susceptibility variants. The CKDGen consortium performed …
[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
[HTML][HTML] The Generation R Study: design and cohort update 2017
…, FC Verhulst, E Wolvius, JF Felix… - European journal of …, 2016 - Springer
The Generation R Study is a population-based prospective cohort study from fetal life until
adulthood. The study is designed to identify early environmental and genetic causes and …
adulthood. The study is designed to identify early environmental and genetic causes and …
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
[HTML][HTML] Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
…, I Persico, JW Jukema, JF Wilson, JF Felix… - Nature …, 2016 - nature.com
Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
…, PJ Thompson, AC Morrison, JF Felix… - JAMA …, 2017 - jamanetwork.com
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
…, E Evangelou, A Evans, T Fall, M Farrall, JF Felix… - Nature …, 2016 - nature.com
To dissect the genetic architecture of blood pressure and assess effects on target organ
damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 …
damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 …