User profiles for J. H. Crichton

James Hugh Crichton

University of Exeter
Verified email at exeter.ac.uk
Cited by 565

[HTML][HTML] Oocyte development, meiosis and aneuploidy

M MacLennan, JH Crichton, CJ Playfoot… - Seminars in cell & …, 2015 - Elsevier
Meiosis is one of the defining events in gametogenesis. Male and female germ cells both
undergo one round of meiotic cell division during their development in order to reduce the …

[HTML][HTML] Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

JH Crichton, DS Dunican, M MacLennan… - Cellular and molecular …, 2014 - Springer
The viability of any species requires that the genome is kept stable as it is transmitted from
generation to generation by the germ cells. One of the challenges to transgenerational …

Radiation torque on a sphere caused by a circularly-polarized electromagnetic wave

PL Marston, JH Crichton - Physical Review A, 1984 - APS
The cross sections associated with absorption, scattering, extinction, and radiation pressure
for homogenous isotropic spheres illuminated by plane waves are well known. We derive a …

The role of chromatin modifications in progression through mouse meiotic prophase

JH Crichton, CJ Playfoot, IR Adams - Journal of genetics and genomics, 2014 - Elsevier
Meiosis is a key event in gametogenesis that generates new combinations of genetic
information and is required to reduce the chromosome content of the gametes. Meiotic …

[PDF][PDF] The measurable distinction between the spin and orbital angular momenta of electromagnetic radiation

JH Crichton, PL Marston - Electronic Journal of Differential …, 2000 - ejde.math.txstate.edu
CRICHTON & PHILIP L. MARSTON … [2] PL Marston and JH Crichton, Radiation torque
on a sphere caused by a circularlypolarized electromagnetic wave, Phys. Rev. A30, 2508 (1984) …

Cluster Decomposition Properties of the Matrix

EH Wichmann, JH Crichton - Physical Review, 1963 - APS
Conditions on the S matrix which arise from the assumption that it describes interactions
which are at least approximately local are discussed. Particular conditions of this kind, which …

Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3

JH Crichton, JM Dunce, OM Dunne… - Nature structural & …, 2023 - nature.com
In meiosis, a supramolecular protein structure, the synaptonemal complex (SC), assembles
between homologous chromosomes to facilitate their recombination. Mammalian SC …

[HTML][HTML] Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells

J Reichmann, JH Crichton, MJ Madej… - PLoS computational …, 2012 - journals.plos.org
Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify
in pluripotent cells or developing germ cells. Host mechanisms that silence …

[HTML][HTML] Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes

JH Crichton, CJ Playfoot, M MacLennan, D Read… - PLoS …, 2017 - journals.plos.org
Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double
strand breaks (DSBs) required for homologous chromosome synapsis and segregation. The …

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning

I Ehrmann, JH Crichton, MR Gazzara, K James, Y Liu… - Elife, 2019 - elifesciences.org
10.7554/eLife.39304.001 Male germ cells of all placental mammals express an ancient
nuclear RNA binding protein of unknown function called RBMXL2. Here we find that deletion of …