Newly diagnosed glioblastoma is now commonly treated with surgery, if feasible, or biopsy,
followed by radiation plus concomitant and adjuvant temozolomide. The treatment of …

BACKGROUND Venous thromboembolism (VTE) frequently complicates the course of
patients with cancer, and there is evidence to suggest that patients with brain tumors are at …

Median age at diagnosis in patients with glioblastoma (GB) is slowly increasing with an aging
population in Western countries, and was 64years in 2006. The number of patients age 65 …

Background Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas are malignant brain
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain-…

Background Glioblastoma is associated with a poor prognosis in the elderly. Survival has
been shown to increase among patients 70 years of age or younger when temozolomide …

Human immunodeficiency virus type 1 (HIV-1)-specific monoclonal antibodies with extraordinary
potency and breadth have recently been described. In humanized mice, combinations …

Adaptive histogram equalization (AHE) and intensity windowing have been compared using
psychophysical observer studies. Experienced radiologists were shown clinical CT (…

The worldwide diversity of HIV-1 presents an unprecedented challenge for vaccine
development 1 , 2 . Antigens derived from natural HIV-1 sequences have elicited only a limited …

Purpose Since 2010, the rate of rural hospital closures has increased significantly. This study
is a preliminary look at recent closures and a formative step in research to understand the …

… Perry et al25 used continuous TMZ 50 mg/m2 in patients with recurrent malignant glioma.
Six-month PFS in patients with GBM who experienced progression on the TMZ 5/28 schedule …