The accurate identification and description of the genes in the human and mouse genomes
is a fundamental requirement for high quality analysis of data informing both genome biology …

Phosphorylation, the most intensively studied and common PTM on proteins, is a complex
biological phenomenon. Its complexity manifests itself in the large numbers of proteins that …

Schizophrenia is a common disease with a complex aetiology, probably involving multiple
and heterogeneous genetic factors. Here, by analysing the exome sequences of 2,536 …

N-methyl-D-aspartate receptors (NMDAR) mediate long-lasting changes in synapse strength
via downstream signaling pathways. We report proteomic characterization with mass …

The combination of affinity purification and tandem mass spectrometry (MS) has emerged as
a powerful approach to delineate biological processes. In particular, the use of epitope tags …

The GENCODE project annotates human and mouse genes and transcripts supported by
experimental data with high accuracy, providing a foundational resource that supports genome …

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and JavaScript. … Jyoti S Choudhary … Jyoti S Choudhary …

We isolated the postsynaptic density from human neocortex (hPSD) and identified 1,461
proteins. hPSD mutations cause 133 neurological and psychiatric diseases and were enriched …

Abstract Characterization of the composition of the postsynaptic proteome (PSP) provides a
framework for understanding the overall organization and function of the synapse in normal …

Lung cancer in East Asia is characterized by a high percentage of never-smokers, early
onset and predominant EGFR mutations. To illuminate the molecular phenotype of this …