User profiles for J. W. Holloway
John W. HollowayUniversity of Southampton Verified email at soton.ac.uk Cited by 24347 |
Genetics of allergic disease
JW Holloway, IA Yang, ST Holgate - Journal of Allergy and Clinical …, 2010 - Elsevier
Allergic diseases are complex genetic diseases resulting from the effect of multiple genetic
and interacting environmental factors on their pathophysiology. Recent years have seen …
and interacting environmental factors on their pathophysiology. Recent years have seen …
The genetic basis of atopic asthma.
JW Holloway, B Beghe, ST Holgate - Clinical and Experimental …, 1999 - iris.unimore.it
Asthma is a respiratory disease characterized by recurrentrespiratory symptoms, reversible
variable airway obstruction,airway inflammation and increased airway responsiveness. …
variable airway obstruction,airway inflammation and increased airway responsiveness. …
Genetic susceptibility to the respiratory effects of air pollution
…, ST Holgate, JW Holloway - Postgraduate …, 2009 - academic.oup.com
There is large variation between individuals in their response to air pollutants. This review
summarises the existing evidence that genetic factors influence the mechanisms of lung injury …
summarises the existing evidence that genetic factors influence the mechanisms of lung injury …
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
…, FM Cuss, S Rorke, JB Clough, JW Holloway… - Nature, 2002 - nature.com
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing,
wheezing and breathlessness. Although environmental factors such as allergen exposure …
wheezing and breathlessness. Although environmental factors such as allergen exposure …
Genome-wide association study identifies five loci associated with lung function
…, JR Britton, RW Morris, JW Holloway… - Nature …, 2010 - nature.com
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
…, PM Lackie, VWV Jaddoe, A Simpson, JW Holloway… - Nature …, 2014 - nature.com
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
[HTML][HTML] Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis
of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult …
of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult …
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Genetic association studies have identified 21 loci associated with atopic dermatitis risk
predominantly in populations of European ancestry. To identify further susceptibility loci for this …
predominantly in populations of European ancestry. To identify further susceptibility loci for this …
Infection of Mice with Mycobacterium bovis–Bacillus Calmette-Guérin (BCG) Suppresses Allergen-induced Airway Eosinophilia
KJ Erb, JW Holloway, A Sobeck, H Moll… - The Journal of …, 1998 - rupress.org
It has been proposed that the increase in prevalence and severity of atopic disorders
inversely correlates with exposure to infectious diseases such as tuberculosis. We have …
inversely correlates with exposure to infectious diseases such as tuberculosis. We have …
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
chronic obstructive pulmonary disease. We tested genome-wide association with forced …