Liquid–liquid phase separation and related phase transitions have emerged as generic
mechanisms in living cells for the formation of membraneless compartments or biomolecular …

Over the past years, numerous methods have emerged to automate the quantification of
animal behavior at a resolution not previously imaginable. This has opened up a new field of …

The desire to understand how the brain generates and patterns behavior has driven rapid
methodological innovation in tools to quantify natural animal behavior. While advances in …

During transcription, RNA polymerase (RNAP) moves processively along a DNA template,
creating a complementary RNA. Here we present the development of an ultra-stable optical …

The need for automated and efficient systems for tracking full animal pose has increased with
the complexity of behavioral data and analyses. Here we introduce LEAP (LEAP estimates …

A frequent assumption in behavioural science is that most of an animal's activities can be
described in terms of a small set of stereotyped motifs. Here, we introduce a method for …

During the past decade, the appreciation and understanding of how bacterial cells can be
organized in both space and time have been revolutionized by the identification and …

Bacterial cells possess multiple cytoskeletal proteins involved in a wide range of cellular
processes. These cytoskeletal proteins are dynamic, but the driving forces and cellular functions …

Escherichia coli RNA polymerase (RNAP) synthesizes RNA with remarkable fidelity in vivo
1 . Its low error rate may be achieved by means of a ‘proofreading’ mechanism comprised of …

The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained
animals is needed to provide new insights into how populations of neurons generate animal …