User profiles for J. Alcami
Jose AlcamiInstituto de Salud Carlos III Verified email at isciii.es Cited by 11565 |
Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs
…, M Perez-Olmeda, J Alcamí - Nature Reviews …, 2009 - nature.com
HIV-1 can infect both activated and resting, non-dividing cells, following which the viral genome
can be permanently integrated into a host cell chromosome. Latent HIV-1 reservoirs are …
can be permanently integrated into a host cell chromosome. Latent HIV-1 reservoirs are …
[HTML][HTML] Overview of SARS-CoV-2 infection in adults living with HIV
…, MA Marcos, E Martínez, S Bertagnolio, J Alcamí… - The lancet HIV, 2021 - thelancet.com
Around 2·5 million deaths and more than 110 million COVID-19 cases have been reported
globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or …
globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or …
Recommendations for measuring HIV reservoir size in cure-directed clinical trials
Therapeutic strategies are being clinically tested either to eradicate latent HIV reservoirs or
to achieve virologic control in the absence of antiretroviral therapy. Attaining this goal will …
to achieve virologic control in the absence of antiretroviral therapy. Attaining this goal will …
[HTML][HTML] Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled …
Background To date, no immunological data on COVID-19 heterologous vaccination schedules
in humans have been reported. We assessed the immunogenicity and reactogenicity of …
in humans have been reported. We assessed the immunogenicity and reactogenicity of …
[HTML][HTML] Membrane raft microdomains mediate lateral assemblies required for HIV‐1 infection
HIV‐1 infection triggers lateral membrane diffusion following interaction of the viral envelope
with cell surface receptors. We show that these membrane changes are necessary for …
with cell surface receptors. We show that these membrane changes are necessary for …
Absolute dependence on kappa B responsive elements for initiation and Tat‐mediated amplification of HIV transcription in blood CD4 T lymphocytes.
J Alcami, T Lain de Lera, L Folgueira… - The EMBO …, 1995 - embopress.org
… DNA in resting CD4 lymphocytes and J-Jhan cells. CD4 T lymphocytes or J-Jhan cells were
… myelomonocytic cells (Arenzana-Seisdedos and Alcami, unpublished results) In order to …
… myelomonocytic cells (Arenzana-Seisdedos and Alcami, unpublished results) In order to …
[HTML][HTML] Hydrogen peroxide increases extracellular matrix mRNA through TGF-β in human mesangial cells
MC Iglesias-De La Cruz, P Ruiz-Torres, J Alcamí… - Kidney international, 2001 - Elsevier
… Carmen Iglesias-de la Cruz , Piedad Ruiz-Torres , José Alcamí , Luisa Díez-Marqués ,
Rocío Ortega-Velázquez , Sheldon Chen , Manuel Rodríguez-Puyol , Fuad N. Ziyadeh , Diego …
Rocío Ortega-Velázquez , Sheldon Chen , Manuel Rodríguez-Puyol , Fuad N. Ziyadeh , Diego …
Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the α subunit of eukaryotic translation initiation factor 2 and NF-κB
The double-stranded (ds) RNA-dependent protein kinase (PKR) is a key mediator of antiviral
effects of interferon (IFN) and an active player in apoptosis induced by different stimuli. The …
effects of interferon (IFN) and an active player in apoptosis induced by different stimuli. The …
Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1
S Michelson, J Alcami, SJ Kim, D Danielpour… - Journal of …, 1994 - Am Soc Microbiol
Human cytomegalovirus (CMV) infection can elicit a transitory, but profound,
immunodepression in immunocompetent individuals. Cytopathogenic destruction of CMV-infected …
immunodepression in immunocompetent individuals. Cytopathogenic destruction of CMV-infected …
Genomic organization and promoter characterization of human CXCR4 gene 1
CXCR4 is the receptor for the CXC chemokine SDF1 that has essential functions on embryo
organogenesis, immunological functions and T lymphocyte trafficking. Recently, CXCR4 …
organogenesis, immunological functions and T lymphocyte trafficking. Recently, CXCR4 …