Among the four G protein–coupled receptors (H 1 –H 4 ) identified as mediators of the
biologic effects of histamine, the H 3 receptor (H 3 R) is distinguished for its almost exclusive …

Since the discovery of the histamine H 3 receptor in 1983, tremendous advances in the
pharmacological aspects of H 3 receptor antagonists/inverse agonists have been accomplished …

J. Neurochem. (2012) 122, 872–882. Abstract The function of histamine in the adult central
nervous system has been extensively studied, but data on its actions upon the developing …

The release of [ 3 H]GABA from slices of rat substantia nigra pars reticulata induced by
increasing extracellular K + from 6 to 15mM in the presence of 10μM sulpiride was inhibited by 73…

Background Particulate matter (PM) adverse effects on health include lung and heart damage.
The renin-angiotensin-aldosterone (RAAS) and kallikrein-kinin (KKS) endocrine systems …

A study was made of the regulation of [ 3 H]‐γ‐aminobutyric acid ([ 3 H]‐GABA) release from
slices of rat striatum by endogenous dopamine and exogenous histamine and a histamine …

The release of glutamate from striatal synaptosomes induced by depolarisation with 4-aminopyridine
(4-AP) was studied by a method based on the fluorescent properties of the NAPDH …

Unilateral 6-hydroxydopamine lesion to rat substantia nigra pars compacta resulted in a
modest, but significant, decrease in the specific binding of N-α-[methyl-3 H] histamine (19±5% …

We have investigated the presence of histamine H 3 receptors (H 3 Rs) on rat thalamic isolated
nerve terminals (synaptosomes) and the effect of their activation on glutamate and GABA …

In striatal membranes bearing significant levels of histamine H 3 receptors (72±14fmol/mg
protein), the H 3 agonist immepip (1μM) increased [ 35 S ]GTPγS binding to 119±2% of basal, …