Machine learning, a collection of data-analytical techniques aimed at building predictive
models from multi-dimensional datasets, is becoming integral to modern biological research. By …

DNA methylation is not just for basic scientists any more. There is a growing awareness in the
medical field that having the correct pattern of genomic methylation is essential for healthy …

In spite of considerable prior research on luxury branding, no widely accepted definition of “luxury
brand” exists. The purpose of this paper is to review the literature in order to: a) …

The reference human genome sequence set the stage for studies of genetic variation and
its association with human disease, but epigenomic studies lack a similar reference. To …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

We report results on the performance of a free-electron laser operating at a wavelength of
13.7 nm where unprecedented peak and average powers for a coherent extreme-ultraviolet …

Primary triple-negative breast cancers (TNBCs), a tumour type defined by lack of oestrogen
receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16…

CpG islands frequently contain gene promoters or exons 1 and are usually unmethylated in
normal cells 1, 2, 3. Methylation of CpG islands is associated with delayed replication, …

The NIH Roadmap Epigenomics Mapping Consortium aims to produce a public resource of
epigenomic maps for stem cells and primary ex vivo tissues selected to represent the normal …

Reconstructing gene regulatory networks from high-throughput data is a long-standing
challenge. Through the Dialogue on Reverse Engineering Assessment and Methods (DREAM) …