User profiles for J. Gagneur

Julien Gagneur

Professor, TUM, Munich
Verified email at in.tum.de
Cited by 12928

[PDF][PDF] Contribution à la connaissance des Ephéméroptères d'Algérie. I. Répartition et écologie (1ère partie)(Insecta, Ephemeroptera)

J Gagneur, AGB Thomas - Bulletin de la …, 1988 - ephemeroptera-galactica.com
48 stations ont été prospectées sur des oueds du Nord-Ouest de l'Algérie entre 1 145 m d'altitude
et le niveau de la mer: 15 espèces d'EphémérOptères ont été récoltées (Baetidae …

Deep learning: new computational modelling techniques for genomics

G Eraslan, Ž Avsec, J Gagneur, FJ Theis - Nature Reviews Genetics, 2019 - nature.com
As a data-driven science, genomics largely utilizes machine learning to capture dependencies
in data and derive novel biological hypotheses. However, the ability to extract new …

Detection of aberrant gene expression events in RNA sequencing data

…, IF Scheller, PF Goldberg, H Prokisch, J Gagneur - Nature protocols, 2021 - nature.com
RNA sequencing (RNA-seq) has emerged as a powerful approach to discover disease-causing
gene regulatory defects in individuals affected by genetically undiagnosed rare disorders…

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

…, Z Avsec, MH Çelik, TYD Nguyen, J Gagneur… - Genome …, 2024 - cris.unibo.it
Background: The Critical Assessment of Genome Interpretation (CAGI) aims to advance the
state-of-the-art for computational prediction of genetic variant impact, particularly where …

[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment

…, A Dilthey, N Fischer, K Förstner, JS Frick, J Gagneur… - Cell, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract infection, however,
a subset of patients progress to severe disease and respiratory failure. The mechanism …

A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

…, K Croughton, C Cruciat, D Eberhard, J Gagneur… - Nature cell …, 2004 - nature.com
Signal transduction pathways are modular composites of functionally interdependent sets of
proteins that act in a coordinated fashion to transform environmental information into a …

[PDF][PDF] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

…, J Gagneur, T Ganzenmueller, M Gauder, J Geißert… - Immunity, 2021 - cell.com
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease (…

The genomic and transcriptomic landscape of a HeLa cell line

…, G Pau, N Delhomme, J Gagneur… - G3: Genes …, 2013 - academic.oup.com
… S Aiyar, Gregoire Pau, Nicolas Delhomme, Julien Gagneur, Jan O Korbel, Wolfgang Huber,
Lars M … We thank J. Ellenberg for providing the HeLa cell line used in this study as well as P. …

Bidirectional promoters generate pervasive transcription in yeast

Z Xu, W Wei, J Gagneur, F Perocchi… - Nature, 2009 - nature.com
… Fritsch for comments on the manuscript, J. Toedling for discussion and for the template of
the website, C. Girardot for data submission to ArrayExpress, N. … Julien Gagneur

[HTML][HTML] Genetic diagnosis of Mendelian disorders via RNA sequencing

…, TM Strom, T Meitinger, J Gagneur… - Nature …, 2017 - nature.com
… counts K i,j of gene i in sample j with a generalized linear … dispersion parameter; s j is the
size factor of sample j; is the … modelled K i,j the number of reads of variant i in sample j as: …