User profiles for J. Galagan

James Galagan

Associate Professor, Boston University
Verified email at bu.edu
Cited by 58525

Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism

…, A Radford, C Selitrennikoff, JE Galagan… - Microbiology and …, 2004 - Am Soc Microbiol
We present an analysis of over 1,100 of the ∼10,000 predicted proteins encoded by the
genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of …

RIP: the evolutionary cost of genome defense

JE Galagan, EU Selker - TRENDS in Genetics, 2004 - cell.com
Repeat-induced point mutation (RIP) is a homology-based process that mutates repetitive
DNA and frequently leads to epigenetic silencing of the mutated sequences through DNA …

Genomics of the fungal kingdom: insights into eukaryotic biology

JE Galagan, MR Henn, LJ Ma, CA Cuomo… - Genome …, 2005 - genome.cshlp.org
… A similar pattern of positional intron loss was revealed by more recent work by Stajich
and colleagues (J. Stajich and FS Dietrich, in prep.). In this analysis, recent intron loss was …

[HTML][HTML] The genome sequence of the filamentous fungus Neurospora crassa

JE Galagan, SE Calvo, KA Borkovich, EU Selker… - Nature, 2003 - nature.com
Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry
and molecular biology. Here, we report a high-quality draft sequence of the N. crassa …

[HTML][HTML] Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium

…, O Yoder, S Young, Q Zeng, S Zhou, J Galagan… - Nature, 2010 - nature.com
Fusarium species are among the most important phytopathogenic and toxigenic fungi. To
understand the molecular underpinnings of pathogenicity in the genus Fusarium, we …

[HTML][HTML] The genome sequence of the rice blast fungus Magnaporthe grisea

…, LJ Ma, R Nicol, S Purcell, C Nusbaum, JE Galagan… - Nature, 2005 - nature.com
Magnaporthe grisea is the most destructive pathogen of rice worldwide and the principal
model organism for elucidating the molecular basis of fungal disease of plants. Here, we report …

[HTML][HTML] Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis

…, S Young, DB Jaffe, S Calvo, C Nusbaum, J Galagan… - Nature, 2006 - nature.com
Ustilago maydis is a ubiquitous pathogen of maize and a well-established model organism
for the study of plant–microbe interactions 1 . This basidiomycete fungus does not use …

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

…, O White, J Woodward, JH Yu, C Fraser, JE Galagan… - Nature, 2005 - nature.com
Aspergillus fumigatus is exceptional among microorganisms in being both a primary and
opportunistic pathogen as well as a major allergen 1 , 2 , 3 . Its conidia production is prolific, …

Genome Sequence of Aedes aegypti, a Major Arbovirus Vector

…, MB Soares, DL Knudson, NH Lee, J Galagan… - Science, 2007 - science.org
We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …

Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

JE Galagan, SE Calvo, C Cuomo, LJ Ma, JR Wortman… - Nature, 2005 - nature.com
The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million
years of evolution. Here we report the genome sequence of the model organism Aspergillus …