User profiles for J. Gurtowski
 | James GurtowskiCold Spring Harbor Laboratory Verified email at columbia.edu Cited by 4502 |
GenomeScope: fast reference-free genome profiling from short reads
GenomeScope is an open-source web tool to rapidly estimate the overall characteristics of a
genome, including genome size, heterozygosity rate and repeat content from unprocessed …
genome, including genome size, heterozygosity rate and repeat content from unprocessed …
[HTML][HTML] KBase: the United States department of energy systems biology knowledgebase
Although similar integrative tools exist (Supplementary Note 2), no other open platform
shares all KBase’s features, which include the following:(i) comprehensive support for data …
shares all KBase’s features, which include the following:(i) comprehensive support for data …
[HTML][HTML] The pineapple genome and the evolution of CAM photosynthesis
Pineapple (Ananas comosus (L.) Merr.) is the most economically valuable crop possessing
crassulacean acid metabolism (CAM), a photosynthetic carbon assimilation pathway with …
crassulacean acid metabolism (CAM), a photosynthetic carbon assimilation pathway with …
Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome
S Goodwin, J Gurtowski, S Ethe-Sayers… - Genome …, 2015 - genome.cshlp.org
Monitoring the progress of DNA molecules through a membrane pore has been postulated
as a method for sequencing DNA for several decades. Recently, a nanopore-based …
as a method for sequencing DNA for several decades. Recently, a nanopore-based …
[HTML][HTML] Whole genome de novo assemblies of three divergent strains of rice, Oryza sativa, document novel gene space of aus and indica
…, LG Maron, JC Stein, AH Wences, J Gurtowski… - Genome biology, 2014 - Springer
… Hybrids of genotype S5-i/S5-j are mostly sterile, whereas hybrids of genotypes consisting
of S5-n with either S5-i or S5-j are mostly fertile. The S5 locus contains three tightly linked …
of S5-n with either S5-i or S5-j are mostly fertile. The S5 locus contains three tightly linked …
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
…, T Garvin, H Fang, J Gurtowski… - Genome …, 2018 - genome.cshlp.org
The SK-BR-3 cell line is one of the most important models for HER2+ breast cancers, which
affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged, although …
affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged, although …
Third-generation sequencing and the future of genomics
Third-generation long-range DNA sequencing and mapping technologies are creating a
renaissance in high-quality genome sequencing. Unlike second-generation sequencing, which …
renaissance in high-quality genome sequencing. Unlike second-generation sequencing, which …
Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano
K Wasik, J Gurtowski, X Zhou… - Proceedings of the …, 2015 - National Acad Sciences
The free-living flatworm, Macrostomum lignano has an impressive regenerative capacity.
Following injury, it can regenerate almost an entirely new organism because of the presence of …
Following injury, it can regenerate almost an entirely new organism because of the presence of …
Error correction and assembly complexity of single molecule sequencing reads
Third generation single molecule sequencing technology is poised to revolutionize
genomics by enabling the sequencing of long, individual molecules of DNA and RNA. These …
genomics by enabling the sequencing of long, individual molecules of DNA and RNA. These …
The DOE systems biology knowledgebase (KBase)
The US Department of Energy Systems Biology Knowledgebase (KBase) is an open-source
software and data platform designed to meet the grand challenge of systems biology — …
software and data platform designed to meet the grand challenge of systems biology — …