Optimum experimental designs

J Kiefer - Journal of the Royal Statistical Society: Series B …, 1959 - Wiley Online Library
After some introductory remarks, we discuss certain basic considerations such as the
nonoptimality of the classical symmetric (balanced) designs for hypothesis testing, the optimality of …

On the nonrandomized optimality and randomized nonoptimality of symmetrical designs

J Kiefer - The Annals of Mathematical Statistics, 1958 - projecteuclid.org
Many commonly employed symmetrical designs such as Balanced Incomplete Block Designs
(BIBD's), Latin Squares (LS's), Youden Squares (YS's), etc., are shown to have optimum …

The equivalence of two extremum problems

J Kiefer, J Wolfowitz - Canadian Journal of Mathematics, 1960 - cambridge.org
Let f1 , …, fk be linearly independent real functions on a space X, such that the range R of (f1,
…, fk) is a compact set in k dimensional Euclidean space. (This will happen, for example, if …

[PDF][PDF] On the theory of queues with many servers

J Kiefer, J Wolfowitz - Transactions of the American …, 1955 - community.ams.org
1. Introduction. The physical original of the mathematical problem to which this paper is devoted
is a system of s" servers," who can be machines in a factory, ticket windows at a railroad …

Epigenetics in development

JC Kiefer - Developmental dynamics: an official publication of …, 2007 - Wiley Online Library
It has become increasingly evident in recent years that development is under epigenetic
control. Epigenetics is the study of heritable changes in gene function that occur independently …

Cyclooxygenase enzymes: catalysis and inhibition

RG Kurumbail, JR Kiefer, LJ Marnett - Current opinion in structural biology, 2001 - Elsevier
Scientists working in the field of cyclooxygenase enzymes have witnessed several major
advances in the past two years. Crystal structures of fatty acid substrate and prostaglandin …

Back to basics: Sox genes

JC Kiefer - Developmental dynamics: an official publication of …, 2007 - Wiley Online Library
Sox genes are indispensable for multiple aspects of development. This primer briefly
describes shared properties of the Sox gene family, and five well‐characterized examples of …

Stochastic estimation of the maximum of a regression function

J Kiefer, J Wolfowitz - The Annals of Mathematical Statistics, 1952 - JSTOR
Let M(x) be a regression function which has a maximum at the unknown point θ. M(x) is itself
unknown to the statistician who, however, can take observations at any level x. This paper …

The COMPASS experiment at CERN

…, B Ketzer, GV Khaustov, YA Khokhlov, J Kiefer… - Nuclear Instruments and …, 2007 - Elsevier
The COMPASS experiment makes use of the CERN SPS high-intensity muon and hadron
beams for the investigation of the nucleon spin structure and the spectroscopy of hadrons. …

Consistency of the maximum likelihood estimator in the presence of infinitely many incidental parameters

J Kiefer, J Wolfowitz - The Annals of Mathematical Statistics, 1956 - JSTOR
… DVORETZKY, J. KIEFER AND J. WOLFOWITZ, "Asymptotic minimax character of the sample
… [4] J. WOLFOWITZ, "Estimation of the components of stochastic structures," Proc. Nat. …