The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an …

Many approaches to identify therapeutically relevant neoantigens couple tumor sequencing
with bioinformatic algorithms and inferred rules of tumor epitope immunogenicity. However, …

In this paper, a methodology for estimating solar potential on multiple building rooftops is
presented. The objective of this methodology is to estimate the daily or monthly solar energy on …

Tumor cells accumulate aberrations not present in normal cells, leading to presentation of
neoantigens on MHC molecules on their surface. These non-self neoantigens distinguish …

Background Web search activity has previously been shown useful for providing estimates
of real-world activity in a variety of contexts, with the most common being health and …

Background Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing
epitope regions optimized for concurrent B cell, CD4 + T cell, and CD8 + T cell stimulation. …

This paper describes the sequencing protocol and computational pipeline for the PGV-001
personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens …

Complement-mediated cytotoxicity may act as a selective pressure for tumor overexpression
of complement regulators. We hypothesize that the same selective pressure could lead to …

OpenVax is a computational workflow for identifying somatic variants, predicting neoantigens,
and selecting the contents of personalized cancer vaccines. It is a Dockerized end-to-end …

Simple Summary This study reports a significant association of pelvic inflammation with
prostate cancer (PCa) aggressiveness in a large cohort of men undergoing robot-assisted …