User profiles for J. Martensson

Johan Mårtensson

Perioperative Medicine and Intensive Care, Karolinska University Hospital Solna
Verified email at sll.se
Cited by 8506

Acute kidney injury in sepsis

…, JA Kellum, C Ronco, R Wald, J Martensson… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous presence
of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU and …

Novel biomarkers of acute kidney injury and failure: clinical applicability

J Mårtensson, CR Martling, M Bell - British journal of …, 2012 - academic.oup.com
Acute kidney injury (AKI) has a number of triggers, including ischaemia, nephrotoxins,
radiocontrast, and bacterial endotoxins. It occurs in around one-third of patients treated in …

The rise and fall of NGAL in acute kidney injury

J Mårtensson, R Bellomo - Blood purification, 2014 - karger.com
For many years, neutrophil gelatinase-associated lipocalin (NGAL) has been considered
the most promising biomarker of acute kidney injury (AKI). Commercial assays and point-of-…

The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies

…, SL Goldstein, K Makris, C Ronco, J Martensson… - Journal of the American …, 2011 - jacc.org
Objectives : The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …

Glutathione deficiency leads to mitochondrial damage in brain.

A Jain, J Mårtensson, E Stole… - Proceedings of the …, 1991 - National Acad Sciences
Glutathione deficiency induced in newborn rats by giving buthionine sulfoximine, a selective
inhibitor of gamma-glutamylcysteine synthetase, led to markedly decreased cerebral cortex …

High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function.

J Mårtensson, JC Lai, A Meister - Proceedings of the …, 1990 - National Acad Sciences
Glutathione, an essential cellular antioxidant required for mitochondrial function, is not
synthesized by mitochondria but is imported from the cytosol. Rat liver mitochondria have a …

Glutathione deficiency decreases tissue ascorbate levels in newborn rats: ascorbate spares glutathione and protects.

J Martensson, A Meister… - Proceedings of the …, 1991 - National Acad Sciences
Glutathione deficiency in newborn rats, produced by administration of L-buthionine-(S,R)-sulfoximine,
a transition-state inactivator of gamma-glutamylcysteine synthetase, decreases …

Glutathione is required for intestinal function.

J Mårtensson, A Jain, A Meister - Proceedings of the …, 1990 - National Acad Sciences
Glutathione (GSH) deficiency produced in mice by giving buthionine sulfoximine leads to
severe degeneration of the epithelial cells of the jejunum and colon. This is prevented by giving …

Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury

J Mårtensson, M Bell, A Oldner, S Xu, P Venge… - Intensive care …, 2010 - Springer
Purpose To study the impact of inflammation/sepsis on the concentrations of neutrophil
gelatinase-associated lipocalin (NGAL) in plasma and urine in adult intensive care unit (ICU) …

Factors related to self-care behaviours in heart failure: A systematic review of European Heart Failure Self-Care Behaviour Scale studies

N Sedlar, M Lainscak, J Mårtensson… - European Journal of …, 2017 - academic.oup.com
Background Self-care is an important element in the comprehensive management of patients
with heart failure. The European Heart Failure Self-Care Behaviour Scale (EHFScBS) was …