User profiles for J. Masel
Joanna MaselProfessor of Ecology & Evolutionary Biology, University of Arizona Verified email at arizona.edu Cited by 5563 |
[HTML][HTML] Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity
Phenotypic plasticity is ubiquitous and generally regarded as a key mechanism for enabling
organisms to survive in the face of environmental change. Because no organism is infinitely …
organisms to survive in the face of environmental change. Because no organism is infinitely …
Robustness: mechanisms and consequences
Biological systems are robust to perturbation by mutations and environmental fluctuations.
New data are shedding light on the biochemical and network-level mechanisms responsible …
New data are shedding light on the biochemical and network-level mechanisms responsible …
Robustness and evolvability
J Masel, MV Trotter - Trends in Genetics, 2010 - cell.com
Why isn't random variation always deleterious? Are there factors that sometimes make
adaptation easier? Biological systems are extraordinarily robust to perturbation by mutations, …
adaptation easier? Biological systems are extraordinarily robust to perturbation by mutations, …
Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
…, GH Sun, M Ma, WC Foo, J Masel… - Proceedings of the …, 2004 - National Acad Sciences
We characterize the survival, migration, and differentiation of human neurospheres derived
from CNS stem cells transplanted into the ischemic cortex of rats 7 days after distal middle …
from CNS stem cells transplanted into the ischemic cortex of rats 7 days after distal middle …
Quantifying the kinetic parameters of prion replication
… A polymer of size i breaks into two pieces of size j and i−j at rate b i,j . Assume that b i,j is a
… In this model we make an additional approximation, namely that b i,j is infinite for i<n. This …
… In this model we make an additional approximation, namely that b i,j is infinite for i<n. This …
[PDF][PDF] Genetic drift
J Masel - Current Biology, 2011 - cell.com
Perhaps, but selection at linked sites also affects rare alleles, whether they are neutral or
under selection. For example, whether a beneficial new mutation appears randomly in a good …
under selection. For example, whether a beneficial new mutation appears randomly in a good …
Non‐CF bronchiectasis: clinical and HRCT evaluation
AB Chang, JP Masel, NC Boyce… - Pediatric …, 2003 - Wiley Online Library
Childhood bronchiectasis not related to underlying disease is still common in some
populations in affluent countries. The aims of the study were to: 1) describe demographics, 2) …
populations in affluent countries. The aims of the study were to: 1) describe demographics, 2) …
Feeding problems in infants with gastro‐oesophageal reflux disease: a controlled study
B Mathisen, L Worrall, J Masel, C Wall… - … of paediatrics and …, 1999 - Wiley Online Library
Objective: Gastro‐oesophageal reflux disease (GORD) in infants is commonly associated
with feeding problems but has not been subject to systematic controlled study. We evaluated …
with feeding problems but has not been subject to systematic controlled study. We evaluated …
The timing of COVID-19 transmission
The timing of SARS-CoV-2 transmission is a critical factor to understand the epidemic trajectory
and the impact of isolation, contact tracing and other non-pharmaceutical interventions …
and the impact of isolation, contact tracing and other non-pharmaceutical interventions …
Young genes are highly disordered as predicted by the preadaptation hypothesis of de novo gene birth
… & Masel, J. Young genes are highly disordered as predicted by the preadaptation hypothesis
of … & Masel, J. The evolution of molecular error rates and the consequences for evolvability. …
of … & Masel, J. The evolution of molecular error rates and the consequences for evolvability. …