User profiles for J. Masel

Joanna Masel

Professor of Ecology & Evolutionary Biology, University of Arizona
Verified email at arizona.edu
Cited by 5563

[HTML][HTML] Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity

…, MA Heskel, JG Kingsolver, HJ Maclean, J Masel… - Heredity, 2015 - nature.com
Phenotypic plasticity is ubiquitous and generally regarded as a key mechanism for enabling
organisms to survive in the face of environmental change. Because no organism is infinitely …

Robustness: mechanisms and consequences

J Masel, ML Siegal - Trends in genetics, 2009 - cell.com
Biological systems are robust to perturbation by mutations and environmental fluctuations.
New data are shedding light on the biochemical and network-level mechanisms responsible …

Robustness and evolvability

J Masel, MV Trotter - Trends in Genetics, 2010 - cell.com
Why isn't random variation always deleterious? Are there factors that sometimes make
adaptation easier? Biological systems are extraordinarily robust to perturbation by mutations, …

Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex

…, GH Sun, M Ma, WC Foo, J Masel… - Proceedings of the …, 2004 - National Acad Sciences
We characterize the survival, migration, and differentiation of human neurospheres derived
from CNS stem cells transplanted into the ischemic cortex of rats 7 days after distal middle …

Quantifying the kinetic parameters of prion replication

J Masel, VAA Jansen, MA Nowak - Biophysical chemistry, 1999 - Elsevier
… A polymer of size i breaks into two pieces of size j and i−j at rate b i,j . Assume that b i,j is a
… In this model we make an additional approximation, namely that b i,j is infinite for i<n. This …

[PDF][PDF] Genetic drift

J Masel - Current Biology, 2011 - cell.com
Perhaps, but selection at linked sites also affects rare alleles, whether they are neutral or
under selection. For example, whether a beneficial new mutation appears randomly in a good …

Non‐CF bronchiectasis: clinical and HRCT evaluation

AB Chang, JP Masel, NC Boyce… - Pediatric …, 2003 - Wiley Online Library
Childhood bronchiectasis not related to underlying disease is still common in some
populations in affluent countries. The aims of the study were to: 1) describe demographics, 2) …

Feeding problems in infants with gastro‐oesophageal reflux disease: a controlled study

B Mathisen, L Worrall, J Masel, C Wall… - … of paediatrics and …, 1999 - Wiley Online Library
Objective: Gastro‐oesophageal reflux disease (GORD) in infants is commonly associated
with feeding problems but has not been subject to systematic controlled study. We evaluated …

The timing of COVID-19 transmission

…, A Nurtay, HY Cheng, TC Ng, HH Lin, R Hinch, J Masel… - MedRxiv, 2020 - medrxiv.org
The timing of SARS-CoV-2 transmission is a critical factor to understand the epidemic trajectory
and the impact of isolation, contact tracing and other non-pharmaceutical interventions …

Young genes are highly disordered as predicted by the preadaptation hypothesis of de novo gene birth

BA Wilson, SG Foy, R Neme, J Masel - Nature ecology & evolution, 2017 - nature.com
… & Masel, J. Young genes are highly disordered as predicted by the preadaptation hypothesis
of … & Masel, J. The evolution of molecular error rates and the consequences for evolvability. …