The p53 tumour suppressor gene
AJ Levine, J Momand, CA Finlay - Nature, 1991 - nature.com
The cell cycle is composed of a series of steps which can be negatively or postively regulated
by various factors. Chief among the negative regulators is the p53 protein. Alteration or …
by various factors. Chief among the negative regulators is the p53 protein. Alteration or …
The MDM2 gene amplification database
J Momand, D Jung, S Wilczynski… - Nucleic acids …, 1998 - academic.oup.com
The p53 tumor suppressor gene is inactivated in human tumors by several distinct mechanisms.
The best characterized inactivation mechanisms are: (i) gene mutation; (ii) p53 protein …
The best characterized inactivation mechanisms are: (i) gene mutation; (ii) p53 protein …
MDM2—master regulator of the p53 tumor suppressor protein
J Momand, HH Wu, G Dasgupta - Gene, 2000 - Elsevier
MDM2 is an oncogene that mainly functions to modulate p53 tumor suppressor activity. In
normal cells the MDM2 protein binds to the p53 protein and maintains p53 at low levels by …
normal cells the MDM2 protein binds to the p53 protein and maintains p53 at low levels by …
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
J Momand, GP Zambetti, DC Olson, D George… - cell, 1992 - cell.com
A cellular phosphoprotein with an apparent molecular mass of 90 kd (p90) that forms a
complex with both mutant and wild-type~ 53 protein has been characterized, purified, and …
complex with both mutant and wild-type~ 53 protein has been characterized, purified, and …
Wild-type p53 binds to the TATA-binding protein and represses transcription.
p53 activates transcription of genes with a p53 response element, and it can repress genes
lacking the element. Here we demonstrate that wild-type but not mutant p53 inhibits …
lacking the element. Here we demonstrate that wild-type but not mutant p53 inhibits …
A rhombohedral ferroelectric phase in epitaxially strained Hf0.5Zr0.5O2 thin films
…, M Salverda, S Matzen, HJ Zhao, J Momand… - Nature materials, 2018 - nature.com
Hafnia-based thin films are a favoured candidate for the integration of robust ferroelectricity
at the nanoscale into next-generation memory and logic devices. This is because their …
at the nanoscale into next-generation memory and logic devices. This is because their …
[HTML][HTML] Interface formation of two-and three-dimensionally bonded materials in the case of GeTe–Sb 2 Te 3 superlattices
GeTe–Sb2Te3 superlattices are nanostructured phase-change materials which are under
intense investigation for non-volatile memory applications. They show superior properties …
intense investigation for non-volatile memory applications. They show superior properties …
Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes.
DC Olson, V Marechal, J Momand, J Chen, C Romocki… - Oncogene, 1993 - europepmc.org
A protein product of the mdm-2 oncogene (p90) has been recently shown to associate with
the protein encoded by the tumor-suppressor gene p53. The mdm-2 gene was originally …
the protein encoded by the tumor-suppressor gene p53. The mdm-2 gene was originally …
Scalable PbS quantum dot solar cell production by blade coating from stable inks
The recent development of phase transfer ligand exchange methods for PbS quantum dots (QD)
has enhanced the performance of quantum dots solar cells and greatly simplified the …
has enhanced the performance of quantum dots solar cells and greatly simplified the …
[PDF][PDF] Mdm-2:“big brother” of p53
J Momand, GP Zambetti - 1997 - escholarship.org
… -2 +/J intercrosses revealed that approximately one-quarter of the embryos (presumably mdm-2
J/J) … Crossing mdm-2 +/J mice with p53 +/J or p53 J/J mice resulted in progeny that were …
J/J) … Crossing mdm-2 +/J mice with p53 +/J or p53 J/J mice resulted in progeny that were …