User profiles for J. Mulvenna

Jason Mulvenna

Verified email at qimrberghofer.edu.au
Cited by 6617

The tumorigenic liver fluke Opisthorchis viverrini–multiple pathways to cancer

B Sripa, PJ Brindley, J Mulvenna, T Laha, MJ Smout… - Trends in …, 2012 - cell.com
Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in
Thailand and adjacent countries. In addition to infection-associated morbidity, infection with O. …

[HTML][HTML] Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos

…, S Kaewkes, E Mairiang, A Loukas, J Mulvenna… - Acta tropica, 2011 - Elsevier
Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in
Thailand and the Lao People's Democratic Republic (Lao PDR; Laos). Currently, more than 600 …

[HTML][HTML] Helminth immunomodulation in autoimmune disease

…, PR Giacomin, A Loukas, JP Mulvenna… - Frontiers in …, 2017 - frontiersin.org
Helminths have evolved to become experts at subverting immune surveillance. Through potent
and persistent immune tempering, helminths can remain undetected in human tissues for …

[HTML][HTML] Genome of the human hookworm Necator americanus

…, A Dougall, ST Gaze, J Mulvenna, J Sotillo… - Nature …, 2014 - nature.com
The hookworm Necator americanus is the predominant soil-transmitted human parasite. Adult
worms feed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, …

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths

…, MV Periago, A Loukas, L Tribolet, J Mulvenna… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Necator americanus Ancylostoma-secreted protein 2 (Na-ASP-2) is secreted
by infective hookworm larvae on entry into human hosts. Vaccination of laboratory animals …

[HTML][HTML] A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

MJ Smout, T Laha, J Mulvenna, B Sripa… - PLoS …, 2009 - journals.plos.org
The human liver fluke, Opisthorchis viverrini, infects millions of people throughout south-east
Asia and is a major cause of cholangiocarcinoma, or cancer of the bile ducts. The …

[HTML][HTML] Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum

J Mulvenna, B Hamilton, SH Nagaraj, D Smyth… - Molecular & Cellular …, 2009 - ASBMB
Hookworms are blood-feeding intestinal parasites of mammalian hosts and are one of the
major human ailments affecting ∼600 million people worldwide. These parasites form an …

[HTML][HTML] Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates

…, J Potriquet, L Becker, D Pickering, J Mulvenna… - International journal for …, 2016 - Elsevier
Herein we show for the first time that Schistosoma mansoni adult worms secrete exosome-like
extracellular vesicles ranging from 50 to 130 nm in size. Extracellular vesicles were …

Discovery, structure and biological activities of the cyclotides

DJ Craik, NL Daly, J Mulvenna… - Current Protein and …, 2004 - ingentaconnect.com
The cyclotides are a family of small disulfide rich proteins that have a cyclic peptide backbone
and a cystine knot formed by three conserved disulfide bonds. The combination of these …

Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype

…, J Potriquet, M Laohaviroj, J Mulvenna… - The Journal of …, 2015 - academic.oup.com
Background. Throughout Asia, there is an unprecedented link between cholangiocarcinoma
and infection with the liver fluke Opisthorchis viverrini. Multiple processes, including chronic …