The IL-4 receptor: signaling mechanisms and biologic functions
▪ Abstract Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation
of immune responses. Its effects depend upon binding to and signaling through a receptor …
of immune responses. Its effects depend upon binding to and signaling through a receptor …
From anchovies to sardines and back: multidecadal change in the Pacific Ocean
FP Chavez, J Ryan, SE Lluch-Cota, M Ñiquen C - science, 2003 - science.org
In the Pacific Ocean, air and ocean temperatures, atmospheric carbon dioxide, landings of
anchovies and sardines, and the productivity of coastal and open ocean ecosystems have …
anchovies and sardines, and the productivity of coastal and open ocean ecosystems have …
Endotoxins and disease mechanisms
DC Morrison, JL Ryan - Annual review of medicine, 1987 - annualreviews.org
In this chapter, current concepts about the mechanisms of action of endo toxin are reviewed.
Particular attention is focused upon endotoxin-induced production of soluble mediators from …
Particular attention is focused upon endotoxin-induced production of soluble mediators from …
On the opportunities and risks of foundation models
AI is undergoing a paradigm shift with the rise of models (eg, BERT, DALL-E, GPT-3) that are
trained on broad data at scale and are adaptable to a wide range of downstream tasks. We …
trained on broad data at scale and are adaptable to a wide range of downstream tasks. We …
Positive youth development in the United States: Research findings on evaluations of positive youth development programs
RF Catalano, ML Berglund, JAM Ryan… - The annals of the …, 2004 - journals.sagepub.com
This article summarizes a much lengthier one that appeared in Prevention and Treatment.
The earlier article grew out of a project initiated by the Department of Health and Human …
The earlier article grew out of a project initiated by the Department of Health and Human …
[HTML][HTML] The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of
symptoms and functional limitations, and have a poor quality of life. By targeting …
symptoms and functional limitations, and have a poor quality of life. By targeting …
Safe handling of nanotechnology
…, K Donaldson, G Oberdörster, MA Philbert, J Ryan… - Nature, 2006 - nature.com
The pursuit of responsible nanotechnologies can be tackled through a series of grand
challenges, argue Andrew D. Maynard and his co-authors.
challenges, argue Andrew D. Maynard and his co-authors.
Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.
…, M Vianna, M Gerlach, J Brett, J Ryan, J Kao… - Journal of Biological …, 1992 - ASBMB
Nonenzymatic glycosylation of proteins, as occurs at an accelerated rate in diabetes, can
lead to the formation of advanced glycosylation end products of proteins (AGEs), which can …
lead to the formation of advanced glycosylation end products of proteins (AGEs), which can …
Quantifying the bullwhip effect in a simple supply chain: The impact of forecasting, lead times, and information
An important observation in supply chain management, known as the bullwhip effect,
suggests that demand variability increases as one moves up a supply chain. In this paper we …
suggests that demand variability increases as one moves up a supply chain. In this paper we …
[PDF][PDF] The impact of COVID-19 on medical education
In the wake of the novel coronavirus (COVID-19) pandemic, it is abundantly clear to all the
necessity of studying the pathology and widespread health consequences associated with the …
necessity of studying the pathology and widespread health consequences associated with the …