Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous
hyper-reactivity to environmental triggers that are innocuous to normal, non-atopic individuals.1 …

Solvents are crucial components in specialty chemical and pharmaceutical industries and in
electrochemical and photoelectrochemical processes, and are increasingly being used in …

… Varghese received his BE degree in chemical engineering from Cooper Union, and his
Ph.D. degree in chemical engineering from the California Institute of Technology. …

OBJECTIVES: To describe the incidence and clinical features of children presenting to
Australian child health specialists with conversion disorder. METHOD: Active, national …

Two potent inhibitors based on the crystal structure of influenza virus sialidase have been
designed. These compounds are effective inhibitors not only of the enzyme, but also of the …

The influenza virus neuraminidase glycoprotein is a tetramer with a box-shaped head, 100×100×60
Å, attached to a slender stalk. The three-dimensional structure of neuraminidase …

Proteolytic processing of the amyloid precursor protein (APP) generates amyloid β (Aβ)
peptide, which is thought to be causal for the pathology and subsequent cognitive decline in …

The catalytic sites of influenza virus neuraminidase are located on the upper corners of the
box-shaped tetramer that forms the head of the molecule. Antigenic determinants form a …

… The authors acknowledge the Intel Foundation for a graduate fellowship (J.-KY), KAUST for
… J.-KY, SM and JRH conceived the work and wrote the manuscript. J.-KY and SM developed …

Crystallographic studies of neuraminidase–sialic acid complexes indicate that sialic acid is
distorted on binding the enzyme. Three arginine residues on the enzyme interact with the …