[HTML][HTML] Comparison of vaccine effectiveness against the omicron (B. 1.1. 529) variant in hemodialysis patients

KJ Spensley, S Gleeson, P Martin, T Thomson… - Kidney international …, 2022 - Elsevier
Results A total of 1121 in-center hemodialysis patients were included in the analysis; all
patients underwent weekly screening for SARS-CoV-2 infection via reverse transcriptase-…

Kidney transplant recipients and omicron: outcomes, effect of vaccines and the efficacy and safety of novel treatments

…, T Thomson, A Thind, M Prendecki, KJ Spensley… - medRxiv, 2022 - medrxiv.org
We aimed to describe the outcomes of Omicron infection in kidney transplant recipients (KTR),
compare the efficacy of the community therapeutic interventions and report the safety …

[HTML][HTML] Lack of seroresponse to SARS-CoV-2 booster vaccines given early post-transplant in patients primed pre-transplantation

S Gleeson, P Martin, T Thomson, KJ Spensley… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 vaccines are recommended pre-transplantation, however, waning immunity
and evolving variants mandate booster doses. Currently there no data to inform the optimal …

[HTML][HTML] Clinical impact of early post-transplant red cell transfusions in kidney transplantation: a systematic review and meta-analysis

…, S Gleeson, T Thomson, KJ Spensley… - Frontiers in …, 2023 - frontiersin.org
Introduction Red blood cell transfusions (RBCT) represent a potentially modifiable risk factor
for HLA sensitisation and adverse outcomes post transplantation. Evidence of the clinical …

[HTML][HTML] Reverse immunodynamics: a new method for identifying targets of protective immunity

KJ Spensley, PS Wikramaratna, BS Penman… - Scientific Reports, 2019 - nature.com
Despite a dramatic increase in our ability to catalogue variation among pathogen genomes,
we have made far fewer advances in using this information to identify targets of protective …

Kidney Transplant Recipients and Omicron: Outcomes, effect of vaccines and the efficacy and safety of novel treatments (preprint)

…, T Thomson, A Thind, M Prendecki, KJ Spensley… - 2022 - pesquisa.bvsalud.org
We aimed to describe the outcomes of Omicron infection in kidney transplant recipients (KTR),
compare the efficacy of the community therapeutic interventions and report the safety …

[PDF][PDF] Renal and Vascular Inflammation Section, Department of Medicine, Imperial College London, Hammersmith Hospital, London, UK* Correspondence to f. tam …

KJ Spensley, FWK Tam - EMJ, 2018 - emjreviews.com
… Dr Spensley has declared no conflicts of interest. … Dr Spensley is supported by a National
Institute for Health Research (NIHR) Biomedical Research Centre funding support bursary. …

[HTML][HTML] Comparison of immunogenicity and clinical effectiveness between BNT162b2 and ChAdOx1 SARS-CoV-2 vaccines in people with end-stage kidney disease …

…, T Thomson, H Edwards, K Spensley… - The Lancet Regional …, 2022 - thelancet.com
Background People with end-stage kidney disease, including people on haemodialysis, are
susceptible to greater COVID-19 related morbidity and mortality. This study compares the …

Copolymerization systems involving reversible propagation steps

KJ Ivin, RH Spensley - Journal of Macromolecular Science …, 1967 - Taylor & Francis
The influence of reversal of propagation reactions on copolymer composition has been
studied for three systems: (1) anionic copolymerization of vinyl mesitylene (M 1 ) and α-…

Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway

…, JH Tan, T Davie, MR Schertzberg, MA Spensley… - Elife, 2019 - elifesciences.org
10.7554/eLife.48165.001 Parasitic helminths infect over a billion humans. To survive in the
low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — …