Although similar integrative tools exist (Supplementary Note 2), no other open platform
shares all KBase’s features, which include the following:(i) comprehensive support for data …

Approaches in molecular biology, particularly those that deal with high-throughput sequencing
of entire microbial communities (the field of metagenomics), are rapidly advancing our …

The fruitfly, Drosophila melanogaster, exhibits many of the cardinal features of sleep, yet little
is known about the neural circuits governing its sleep 1 . Here we have performed a screen …

The soil ecosystem is critical for human health, affecting aspects of the environment from key
agricultural and edaphic parameters to critical influence on climate change. Soil has more …

MG-RAST ( http://metagenomics.anl.gov ) is an open-submission data portal for processing,
analyzing, sharing and disseminating metagenomic datasets. The system currently hosts …

Adult behavioral assays have been used with great success in Drosophila melanogaster to
identify circadian rhythm genes. In particular, the locomotor activity assay can identify altered …

Background Preterm infants represent a unique patient population that is born functionally
immature and must accomplish development under the influence of a hospital environment. …

Gene transcription is a central timekeeping process in animal clocks. In Drosophila, the
basic helix-loop helix (bHLH)-PAS transcription-factor heterodimer, CLOCK/CYCLE (CLK/CYC), …

Circadian rhythms of behavior, physiology, and gene expression are present in diverse
tissues and organisms. The function of the transcriptional activator, Clock, is necessary in both …

… (Independent reproduction of the technique by two parties [Keegan and McDonald] identified
136 probe sets, these include 132 of the originally reported 135 probe sets, and four probe …