Pancreatic cancer is an aggressive malignancy with a poor prognosis. The disease and its
treatment can cause significant nutritional impairments that often adversely impact patient …

Genome-wide association studies (GWAS) have identified thousands of variants robustly
associated with complex traits. However, the biological mechanisms underlying these …

Scalable, integrative methods to understand mechanisms that link genetic variants with
phenotypes are needed. Here we derive a mathematical expression to compute PrediXcan (a …

Background Horizontal transmission of bacteria, especially multidrug-resistant organisms (MDROs),
remains an important concern in hospitals worldwide. Some studies have implicated …

Pelvic radiation therapy is an integral component in the treatment of various gastrointestinal,
gynecologic, and genitourinary cancers. As survival rates from these malignancies improve, …

During the ongoing COVID-19 pandemic, there have been many fundamental changes to
the health care system, one of which has been the rapid adoption of telehealth. 1 Despite …

Understanding the genetic architecture of gene expression traits is key to elucidating the
underlying mechanisms of complex traits. Here, for the first time, we perform a systematic …

Genomic analysis of paired tumor–normal samples and clinical data can be used to match
patients to cancer therapies or clinical trials. We analyzed 500 patient samples across diverse …

Mammographic density reflects the amount of stromal and epithelial tissues in relation to
adipose tissue in the breast and is a strong risk factor for breast cancer. Here we report the …

A retrospective study was conducted to find out the causative agents of urinary tract infection
(UTI) in children and their antibiotic sensitivity pattern among Nepalese children. This was …