We present HiGlass, an open source visualization tool built on web technologies that
provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps …

Most invasive bacterial infections are caused by species that more commonly colonize the
human host with minimal symptoms. Although phenotypic or genetic correlates underlying a …

… However, commercial (dry, denatured) HA did not competitively block collagen binding at
all after reconstitution in solution (K. Dinkla, unpublished observations). This may be due to …

We present Kelp Diagrams, a novel method to depict set relations over points, ie, elements
with predefined positions. Our method creates schematic drawings and has been designed to …

… purification of four recombinant proteins spanning P159 (F1 P159 , F2 P159 , F3 P159
and F4 P159 ), only F3 P159 and F4 P159 bound heparin in a dose‐dependent manner (K d …

The human protease plasmin plays a crucial role in the capacity of the group A streptococcus
(Streptococus pyogenes; GAS) to initiate invasive disease. The GAS strain NS88. 2 was …

… M49, the parental Cpa-expressing strain, did not bind or recruit soluble CIV or CI, and direct
binding strains as well as the majority of the recruiting isolates lack the cpa gene (K. Dinkla, …

We present a novel technique-Compressed Adjacency Matrices-for visualizing gene
regulatory networks. These directed networks have strong structural characteristics: out-degrees …

One of the major problems associated with the development of a vaccine against Streptococcus
pyogenes is the ability of this pathogen to escape recognition by antibodies directed …

… 2D), with apparent dissociation constants of K d = 5×10 −9 M and K d = 6×10 −8 M,
respectively. Taken together the results demonstrate a direct and specific interaction between M3-…