User profiles for K. Ellrott

Kyle Ellrott

Oregon Health and Science University
Verified email at ohsu.edu
Cited by 41093

[HTML][HTML] The cancer genome atlas pan-cancer analysis project

…, GB Mills, KR Shaw, BA Ozenberger, K Ellrott… - Nature …, 2013 - nature.com
The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large
numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and …

[HTML][HTML] Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines

K Ellrott, MH Bailey, G Saksena, KR Covington… - Cell systems, 2018 - cell.com
The Cancer Genome Atlas (TCGA) cancer genomics dataset includes over 10,000 tumor-normal
exome pairs across 33 different cancer types, in total >400 TB of raw data files requiring …

[PDF][PDF] GA4GH: International policies and standards for data sharing across genomic research and healthcare

…, LJ Dursi, SOM Dyke, JA Eddy, K Eilbeck, KP Ellrott… - Cell genomics, 2021 - cell.com
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical
advances by enabling the responsible sharing of clinical and genomic data through both …

[HTML][HTML] Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

AD Ewing, KE Houlahan, Y Hu, K Ellrott, C Caloian… - Nature …, 2015 - nature.com
… At each rank k, the gray dot indicates performance of the ensemble algorithms ranking 1
to k, and the colored dot indicates the performance of the algorithm at that rank. …

Mechanisms of streptomycin resistance: selection of mutations in the 16S rRNA gene conferring resistance

…, YG Kidan, T Prammananan, K Ellrott… - Antimicrobial agents …, 2001 - Am Soc Microbiol
Chromosomally acquired streptomycin resistance is frequently due to mutations in the gene
encoding the ribosomal protein S12,rpsL. The presence of several rRNA operons (rrn) and a …

[PDF][PDF] Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space

…, E Banks, VJ Carey, RJ Carroll, A Culotti, K Ellrott… - Cell Genomics, 2022 - cell.com
The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL;
https://anvilproject.org) was developed to address a widespread community need for a …

The UCSC cancer genomics browser: update 2013

M Goldman, B Craft, T Swatloski, K Ellrott… - Nucleic acids …, 2013 - academic.oup.com
The UCSC Cancer Genomics Browser ( https://genome-cancer.ucsc.edu/ ) is a set of web-based
tools to display, investigate and analyse cancer genomics data and its associated …

[HTML][HTML] A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

…, C del Vecchio Fitz, BA Pitel, OU Sezerman, K Ellrott… - Nature …, 2020 - nature.com
Precision oncology relies on accurate discovery and interpretation of genomic variants,
enabling individualized diagnosis, prognosis and therapy selection. We found that six prominent …

[HTML][HTML] Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas

L Omberg, K Ellrott, Y Yuan, C Kandoth, C Wong… - Nature …, 2013 - nature.com
… LO, KE and AAM wrote the manuscript with assistance from CK, SHF, JS and HLLO, KE
and CW created the visuals for the manuscript. LO and KE coordinated data aggregation and …

TumorMap: exploring the molecular similarities of cancer samples in an interactive portal

…, AS Weinstein, R Baertsch, SR Salama, K Ellrott… - Cancer research, 2017 - AACR
Vast amounts of molecular data are being collected on tumor samples, which provide
unique opportunities for discovering trends within and between cancer subtypes. Such cross-…