User profiles for K. Franze

Kristian Franze

Institute of Medical Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg
Verified email at fau.de
Cited by 9867

Mechanics in neuronal development and repair

K Franze, PA Janmey, J Guck - Annual review of biomedical …, 2013 - annualreviews.org
Biological cells are well known to respond to a multitude of chemical signals. In the nervous
system, chemical signaling has been shown to be crucially involved in development, normal …

The mechanical control of nervous system development

K Franze - Development, 2013 - journals.biologists.com
The development of the nervous system has so far, to a large extent, been considered in the
context of biochemistry, molecular biology and genetics. However, there is growing …

The biophysics of neuronal growth

K Franze, J Guck - Reports on Progress in Physics, 2010 - iopscience.iop.org
For a long time, neuroscience has focused on biochemical, molecular biological and
electrophysiological aspects of neuronal physiology and pathology. However, there is a growing …

Müller cells are living optical fibers in the vertebrate retina

K Franze, J Grosche, SN Skatchkov… - Proceedings of the …, 2007 - National Acad Sciences
Although biological cells are mostly transparent, they are phase objects that differ in shape
and refractive index. Any image that is projected through layers of randomly oriented cells will …

Mechanosensing is critical for axon growth in the developing brain

…, M Viana, LF Costa, J Guck, CE Holt, K Franze - Nature …, 2016 - nature.com
During nervous system development, neurons extend axons along well-defined pathways.
The current understanding of axon pathfinding is based mainly on chemical signaling. …

Viscoelastic properties of individual glial cells and neurons in the CNS

YB Lu, K Franze, G Seifert… - Proceedings of the …, 2006 - National Acad Sciences
One hundred fifty years ago glial cells were discovered as a second, non-neuronal, cell type
in the central nervous system. To ascribe a function to these new, enigmatic cells, it was …

Niche stiffness underlies the ageing of central nervous system progenitor cells

…, A Sharma, S Holmqvist, DH Rowitch, K Franze… - Nature, 2019 - nature.com
… i–k, Overview and quantifications of the differentiation rates of aOPCs, following the
injection of DMSO or 5 µM blebbistatin, at 14 days post-lesion in lesions induced by toxin (ethidium …

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

…, A Warren, V Gnanapragasam, E Gottlieb, K Franze… - Nature, 2016 - nature.com
… The ligation mixture was then incubated with Proteinase K (Roche) at 65 C overnight to
reverse the crosslinking and was incubated with RNase A (Roche) at 37 C for 1 h. DNA was …

[HTML][HTML] The soft mechanical signature of glial scars in the central nervous system

…, B Haenzi, EJ Bradbury, J Fawcett, K Franze - Nature …, 2017 - nature.com
Injury to the central nervous system (CNS) alters the molecular and cellular composition of
neural tissue and leads to glial scarring, which inhibits the regrowth of damaged axons. …

Metastable underwater superhydrophobicity

R Poetes, K Holtzmann, K Franze, U Steiner - Physical review letters, 2010 - APS
Superhydrophobicity is generally considered to be a thermodynamically stable wetting state.
The stability of the plastron (the thin air film separating the substrate from the water in the …