The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Bioconductor is an open-source, open-development software project for the analysis and
comprehension of high-throughput data in genomics and molecular biology. The project aims …

Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the mammalian
central nervous system, are mediated via signaling by ionotropic glutamate receptors (…

Six DNA regions were evaluated as potential DNA barcodes for Fungi, the second largest
kingdom of eukaryotic life, by a multinational, multilaboratory consortium. The region of the …

… However, we have developed a method that uses ∼170 000 open sea probes on the
450 k to detect long-range changes in the methylation status. To do this, we first use the …

The ancestors of fungi are believed to be simple aquatic forms with flagellated spores,
similar to members of the extant phylum Chytridiomycota (chytrids). Current classifications …

To evaluate the timing of mutations in BRAF (v-raf murine sarcoma viral oncogene homolog
B1) during melanocytic neoplasia, we carried out mutation analysis on microdissected …

Purpose Older adults are vulnerable to chemotherapy toxicity; however, there are limited data
to identify those at risk. The goals of this study are to identify risk factors for chemotherapy …

High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful
new tools for investigating a wide range of biological and medical questions. Statistical …

The Polycomb group (PcG) proteins form chromatin-modifying complexes that are essential
for embryonic development and stem cell renewal and are commonly deregulated in cancer. …