The fine-scale genetic structure of the British population

…, G Hellenthal, D Davison, A Boumertit, T Day, K Hutnik… - Nature, 2015 - nature.com
… used for classification (K). To understand the method in the simplest cases we set K = 2 and
K = 3, and for comparison to the results presented in our main analyses we set K = 17. The …

[HTML][HTML] People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population

…, I Evseeva, K Hutnik, S Leslie, K Nicodemus… - European Journal of …, 2012 - nature.com
There is a great deal of interest in a fine-scale population structure in the UK, both as a
signature of historical immigration events and because of the effect population structure may …

Genetics of the human face: Identification of large-effect single gene variants

…, WP Koppen, WJ Christmas, K Hutnik… - Proceedings of the …, 2018 - National Acad Sciences
… for all k = 1,2,3...m, where ε k represents the effects of the environment. We assume that E e
k |… predictive influence of variable X k on Y j , we minimize the expected least-squares error, …

2, 4-D and MCPA and their derivatives: effect on the activity of membrane erythrocytes acetylcholinesterase (in vitro)

B Bukowska, K Hutnik - Pesticide Biochemistry and Physiology, 2006 - Elsevier
K m and V max were calculated from the Michaelis curve. Statistically significant decrease of
V max and K m was … 2,4-D decreases V max but do not change K m value, what reveals non-…

[HTML][HTML] The Irish DNA Atlas: revealing fine-scale population structure and history within Ireland

…, AM Molloy, LC Brody, W Bodmer, K Hutnik… - Scientific reports, 2017 - nature.com
… At k = 48 we reproduce previously reported genetic structure across Britain 21 , … k = 30, and
all clusters at this level have a minimum size of 10 individuals (Supplementary Table 1). At k

[HTML][HTML] Sequencing of autosomal, mitochondrial and Y-chromosomal forensic markers in the People of the British Isles cohort detects population structure dominated …

TI Huszar, WF Bodmer, K Hutnik, JH Wetton… - Forensic Science …, 2022 - Elsevier
… For both data types, the most likely value of k (cluster number) = 1, indicating a lack of
population structure, and visual inspection of cluster plots at higher values of k confirms this (data …

Ocena porównawcza kombajnu zbożowego New Holland CS 6070 z kombajnem Bizon Rekord Z-058

F Molendowski, L Romański, K Hutnik - Inżynieria Rolnicza, 2011 - yadda.icm.edu.pl
Przeprowadzono ocenę porównawczą wskaźników eksploatacyjnych kombajnu zbożowego
nowej generacji New Holland CS 6070, w którym wprowadzono nowe rozwiązania …

[PDF][PDF] ACETYLO-I BUTYRYLOCHOLINOESTERAZA–budowa, funkcje i ich inhibitory

B Bukowska, D Pieniążek, K Hutniki, W Duda - Curr. Top. Biophys, 2007 - researchgate.net
Cholinesterases are divided into two enzyme classes according to their substrate specificity,
behaviour towards excess substrate and susceptibility to inhibitors: acetylcholinesterase (…

[HTML][HTML] Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

…, E Johnstone, S Tonks, T Day, K Hutnik… - Journal of human …, 2012 - nature.com
Some 15–20% of multiple adenomatous polyposis have no genetic explanation and 20–30%
of colorectal cancer (CRC) cases are thought to be due to inherited multifactorial causes. …

[HTML][HTML] Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients

…, S Tonks, C Colas, T Day, K Hutnik… - Journal of human …, 2011 - nature.com
We examined the influence that rare variants and low-frequency polymorphisms in the cancer
candidate gene CCND1 have on the development of multiple intestinal adenomas and the …