Background Improvements to prognostic models in metastatic castration-resistant prostate
cancer have the potential to augment clinical trial design and guide treatment strategies. In …

Purpose Docetaxel has a demonstrated survival benefit for patients with metastatic
castration-resistant prostate cancer (mCRPC); however, 10% to 20% of patients discontinue …

Ovarian cancer relapse is often characterized by metastatic spread throughout the peritoneal
cavity with tumors attached to multiple organs. In this study, interaction of ovarian cancer …

In ovarian cancer, metastasis is typically confined to the peritoneum. Surgical removal of the
primary tumor and macroscopic secondary tumors is a common practice, but more effective …

… For more explicit descriptions of the cellular Potts model for modeling drug delivery in
tumors, please see Kanigel Winner, et al.,33 and Extended Methods are available at https://…

… My mother, Vivian Kay Kanigel, cared for my son for 7 months before my defense; my
sister and brother-in-law, Kara and Trent Copanas, have welcomed us into their home as we …

Short Abstract—In ovarian cancer, the morphology of microscopic tumors depends on local
characteristics of tissues to which cells initially attach in the peritoneal cavity. We use an …

Background Docetaxel has a demonstrated survival benefit for metastatic castration-resistant
prostate cancer (mCRPC). However, 10-20% of patients discontinue docetaxel prematurely …

The FAIR data guiding principles have been recently developed and widely adopted to improve
the Findability, Accessibility, Interoperability, and Reuse of digital assets in the face of an …

Kimberly Rene Kanigel Winner Biology This dissertation is approved, and it is acceptable in …
My mother, Vivian Kay Kanigel, cared for my son for 7 months before my defense; my sister …