… AM Gülmezoglu and KS Khan coordinated the analysis and writing of the manuscript.
PFA Van Look reviewed and provided input into the manuscript. All authors contributed …

… Analysis and interpretation of data: Woolcott, Richardson, Khan, and Marra. Drafting of
the manuscript: Woolcott, Richardson, Patel, and Khan. Critical revision of the manuscript for …

Systematic reviews and meta-analyses are a key element of evidence-based healthcare, yet
they remain in some ways mysterious. Why did the authors select certain studies and reject …

Amyloid-β peptide (Aβ) seems to have a central role in the neuropathology of Alzheimer's
disease (AD) 1 . Familial forms of the disease have been linked to mutations in the amyloid …

One hallmark of Alzheimer disease is the accumulation of amyloid β-peptide in the brain
and its deposition as plaques. Mice transgenic for an amyloid β precursor protein (APP) mini-…

… Here, N is the probability density function of a normal distribution with mean μ – f and
standard deviation σ, and k and x 50 are the parameters of the logistic function relating …

ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual failure in
aged humans. AD brains contain numerous amyloid plaques surrounded by dystrophic …

BACKGROUND The cyclooxygenase (COX) enzyme catalyzes the formation of prostaglandins,
which can affect cell proliferation and alter the response of the immune system to …

In 1985 when a group of experts convened by the World Health Organization in Fortaleza,
Brazil, met to discuss the appropriate technology for birth, they echoed what at that moment …

Patient-derived organoids (PDOs) have recently emerged as robust preclinical models;
however, their potential to predict clinical outcomes in patients has remained unclear. We report …