User profiles for K. Le Cao
Kim-Anh Lê CaoUniversity of Melbourne Verified email at unimelb.edu.au Cited by 12003 |
[HTML][HTML] mixOmics: An R package for 'omics feature selection and multiple data integration
… in the Results Section), we found that K − 1 components, where K is the number of classes,
was … However, assessing the performance of a non sparse model with K to K + 2 components …
was … However, assessing the performance of a non sparse model with K to K + 2 components …
Multivariate analysis of multiple datasets: a practical guide for chemical ecology
Chemical ecology has strong links with metabolomics, the large-scale study of all metabolites
detectable in a biological sample. Consequently, chemical ecologists are often challenged …
detectable in a biological sample. Consequently, chemical ecologists are often challenged …
Statistical challenges in longitudinal microbiome data analysis
… k-medoids clustering [53], whereby data are allocated into k clusters (similar to … Kim-Anh
Lê Cao is associate professor in Statistical Genomics. Her laboratory focuses on the …
Lê Cao is associate professor in Statistical Genomics. Her laboratory focuses on the …
[HTML][HTML] Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems
… K - 1 (K - 2) dimensions is sufficient to explain the covariance structure of the microarray (SNP)
data. In the following, we only record the classification error rate obtained after K - 1 (K - 2…
data. In the following, we only record the classification error rate obtained after K - 1 (K - 2…
A sparse PLS for variable selection when integrating omics data
KA Lê Cao, D Rossouw, C Robert-Granié… - … applications in genetics …, 2008 - degruyter.com
… The first and rather straightforward way is to use k-fold cross validation or leave-one-out
cross validation and compute the prediction error (“RMSEP” see section 1.6.3) in order to …
cross validation and compute the prediction error (“RMSEP” see section 1.6.3) in order to …
DIABLO: an integrative approach for identifying key molecular drivers from multi-omics assays
… As the class prediction relies on individual vote from each omics set, DIABLO allows for
some missing datasets X k during the prediction step, as illustrated in the Breast Cancer case …
some missing datasets X k during the prediction step, as illustrated in the Breast Cancer case …
integrOmics: an R package to unravel relationships between two omics datasets
KA Lê Cao, I González, S Déjean - Bioinformatics, 2009 - academic.oup.com
Motivation: With the availability of many ‘omics’ data, such as transcriptomics, proteomics or
metabolomics, the integrative or joint analysis of multiple datasets from different technology …
metabolomics, the integrative or joint analysis of multiple datasets from different technology …
Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients
In animals, immunomodulatory dendritic cells (DCs) exposed to autoantigen can suppress
experimental arthritis in an antigen-specific manner. In rheumatoid arthritis (RA), disease-…
experimental arthritis in an antigen-specific manner. In rheumatoid arthritis (RA), disease-…
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
Evolutionary change in gene expression is generally considered to be a major driver of
phenotypic differences between species. We investigated innate immune diversification by …
phenotypic differences between species. We investigated innate immune diversification by …
[HTML][HTML] Sparse canonical methods for biological data integration: application to a cross-platform study
… We focus on two-block data matrices denoted X(n × p) and Y (n × q), where the p variables
x j and q variables y k are of two types and measured on the same samples or individuals n, …
x j and q variables y k are of two types and measured on the same samples or individuals n, …