… The cost for the insertion of length k starting at position p is defined as:(9) G i (p,k)=G p i,i
+(k−1)×G p i,e There are four categories of insertion according to its position relative to …

Three enzymes, peptidyl-arginine deiminase from Porphyromonas gingivalis, arginine
deiminase and amidinotransferase are traditionally classified separately. By combining PSI-…

Highlights • Protein–protein interactions (PPIs) have emerged as promising targets for drug
discovery. • PPI network (PPIN)-based analyses can reveal genotype–phenotype …

Disrupted in Schizophrenia 1 (DISC1) is a schizophrenia risk gene associated with cognitive
deficits in both schizophrenics and the normal ageing population. In this study, we have …

The gut microbiome is an important determinant in various diseases. Here we perform a
cross-sectional study of Japanese adults and identify the Blautia genus, especially B. wexlerae, …

… Because k varies with for a given power density, τ e V (equation (2)), for each rock type we
plotted curves of reaction speed constant for the highest and lowest values of (Methods). In b, …

We describe a database of protein structure alignments for homologous families. The database
HOMSTRAD presently contains 130 protein families and 590 aligned structures, which …

The voltage-sensitive sodium channel confers electrical excitability on neurons, a fundamental
property required for higher processes including cognition. The ion-conducting α-subunit …

… also been incorporated, such as RNAi data, orthologue data generated by InParanoid [45,
46] and three-dimensional protein structural domain predictions (K Mizuguchi, unpublished). …

… us to identify several key residues including this glutamine, which are conserved in these
proteins, and this led to a hypothesis that Spätzle is also a member of this family (Mizuguchi et …