In vertebrates, including humans, individuals harbor gut microbial communities whose
species composition and relative proportions of dominant microbial groups are tremendously …

The Collaborative Cross (CC) is a mouse recombinant inbred strain panel that is being
developed as a resource for mammalian systems genetics. Here we describe an experiment that …

Background Individuality in the species composition of the vertebrate gut microbiota is
driven by a combination of host and environmental factors that have largely been studied …

Dysregulation of the dopamine system is linked to various aberrant behaviors, including
addiction, compulsive exercise, and hyperphagia leading to obesity. The goal of the present …

An insertion polymorphism of the angiotensin-I converting enzyme gene (ACE) is common
in humans and the higher expressing allele is associated with an increased risk of diabetic …

An overactive renin-angiotensin system is associated with obesity and the metabolic
syndrome. However, the mechanisms behind it are unclear. Cleaving angiotensinogen to …

Adipogenesis plays a critical role in the initiation and progression of obesity. Although
cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) have emerged as a potential …

Significant departures from expected Mendelian inheritance ratios (transmission ratio
distortion, TRD) are frequently observed in both experimental crosses and natural populations. …

Aging is associated with declining exercise and unhealthy changes in body composition.
Exercise ameliorates certain adverse age‐related physiological changes and protects against …

… Kunjie Hua , Kunjie Hua … William T Barrington, Phillip Wulfridge, Ann E Wells, Carolina
Mantilla Rojas, Selene YF Howe, Amie Perry, Kunjie Hua, Michael A Pellizzon, Kasper D Hansen, …