Stimulation of both aerobic glycolysis and Na+-K+-ATPase activity in skeletal muscle by epinephrine or amylin

…, A Balasubramaniam, LA Friend… - American Journal …, 1999 - journals.physiology.org
Epinephrine and amylin stimulate glycogenolysis, glycolysis, and Na + -K + -ATPase activity
in skeletal muscle. However, it is not known whether these hormones stimulate glycolytic …

Hypoxia is not the sole cause of lactate production during shock

FA Luchette, WA Jenkins, LA Friend, C Su… - Journal of Trauma …, 2002 - journals.lww.com
Background Traditionally, elevated blood lactate after hemorrhage is interpreted as tissue
hypoperfusion, hypoxia, and anaerobic glycolysis. The severity and duration of the increase in …

Adrenergic blockade reduces skeletal muscle glycolysis and Na+, K+-ATPase activity during hemorrhage

…, JH James, FA Luchette, L Wang, LA Friend… - Journal of Surgical …, 2001 - Elsevier
Background. Recent evidence suggests that hyperlactatemia in shock may reflect
accelerated aerobic glycolysis linked to activity of the Na + , K + -ATPase rather than hypoxia. …

Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats

S Sheriff, N Kadeer, R Joshi, LA Friend… - Molecular and cellular …, 2012 - Elsevier
Although ghrelin and GHRP-2 have been shown to inhibit skeletal muscle proteolysis in rats
with burn injury, the effects of des-acyl ghrelin (DAG) have not been reported. In this paper, …

Macrophage-derived chemokine (CCL22) is a novel mediator of lung inflammation following hemorrhage and resuscitation

JR Richter, JM Sutton, RM Belizaire, LA Friend… - Shock, 2014 - journals.lww.com
Resuscitation of patients after hemorrhage often results in pulmonary inflammation and places
them at risk for the development of acute respiratory distress syndrome. Our previous data …

Microparticles impact coagulation after traumatic brain injury

EF Midura, PL Jernigan, JW Kuethe, LA Friend… - Journal of Surgical …, 2015 - Elsevier
Background The pathophysiology that drives the subacute hypercoagulable state commonly
seen after traumatic brain injury (TBI) is not well understood. Alterations caused by TBI in …

Impact of tranexamic acid on coagulation and inflammation in murine models of traumatic brain injury and hemorrhage

RM Boudreau, M Johnson, R Veile, LA Friend… - Journal of Surgical …, 2017 - Elsevier
Background Posttraumatic coagulopathy and inflammation can exacerbate secondary
cerebral damage after traumatic brain injury (TBI). Tranexamic acid (TXA) has been shown …

Remember when... Memory-work as an interpretive methodology for sport management

P Markula, LA Friend - Journal of Sport Management, 2005 - journals.humankinetics.com
… This method has been previously employed in marketing research (Friend, 1997), and we
believe that sport management can derive parallel benefits from its interpretive and critical …

Ghrelin inhibits skeletal muscle protein breakdown in rats with thermal injury through normalizing elevated expression of E3 ubiquitin ligases MuRF1 and MAFbx

…, R Joshi, C Su, LA Friend… - American Journal …, 2009 - journals.physiology.org
We previously determined that ghrelin synthesis was downregulated after burn injury and
that exogenous ghrelin retained its ability both to stimulate food intake and to restore plasma …

Role of skeletal muscle Na+–K+ ATPase activity in increased lactate production in sub–acute sepsis

…, SR Nierman, JH James, L Wang, JK King, LA Friend… - Life sciences, 2002 - Elsevier
Bacterial sepsis is frequently accompanied by increased blood concentration of lactic acid,
which traditionally is attributed to poor tissue perfusion, hypoxia and anaerobic glycolysis. …