Background This study aims to examine the worldwide prevalence of post-coronavirus
disease 2019 (COVID-19) condition, through a systematic review and meta-analysis. Methods …

Genetic and genomic studies have enhanced our understanding of complex neurodegenerative
diseases that exert a devastating impact on individuals and society. One such disease, …

Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts
for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying …

Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

Age-related macular degeneration (AMD) is a multifactorial disease and a prevalent cause
of visual impairment in developed countries. Risk factors include environmental components …

Variation in the apolipoprotein E gene (APOE) has been reported to be associated with
longevity in humans. The authors assessed the allelic distribution of APOE isoforms ε2, ε3, and …

In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks,
most binary traits have substantially fewer cases than controls. Both of the widely used …

Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

To identify genetic variation underlying atrial fibrillation, the most common cardiac arrhythmia,
we performed a genome-wide association study of >1,000,000 people, including 60,620 …