Cisplatin-based chemotherapy is the standard treatment of choice for head and neck
squamous cell carcinoma (HNSCC). The efficiency of platinum-based therapies is directly …

Circulating platelets roll along exposed collagen at vessel injury sites and respond with
filipodia protrusion, shape change, and surface area expansion to facilitate platelet adhesion …

Complete sequencing of the Xylella fastidiosa genome revealed characteristics that have not
been described previously for a phytopathogen. One characteristic of this genome was the …

Current knowledge about Periostin biology has expanded from its recognized functions in
embryogenesis and bone metabolism to its roles in tissue repair and remodeling and its …

Ghrelin is a hormone secreted by the stomach during fasting periods and acts through its
receptor, the growth hormone secretagogue 1a (GHSR1a), to promote food intake and prevent …

Western blotting experiments were initially performed to detect a target protein in a complex
biological sample and more recently, to measure relative protein abundance. …

Defective endocytosis and vesicular trafficking of signaling receptors has recently emerged
as a multifaceted hallmark of malignant cells. Clathrin-coated pits (CCPs) display highly …

Tissue integrity requires constant maintenance of a quiescent, yet responsive, population of
stem cells. In the skin, hair follicle stem cells (HFSCs) that reside within the bulge maintain …

Recent research has implicated endocytic pathways as important regulators of receptor
signaling. However, the role of endocytosis in regulating chemokine CXC receptor 4 (CXCR4) …

Xylella fastidiosa strain 9a5c is a gram-negative phytopathogen that is the causal agent of
citrus variegated chlorosis (CVC), a disease that is responsible for economic losses in …