In computational biology and other sciences, researchers are frequently faced with a choice
between several computational methods for performing data analyses. Benchmarking …

DNA methylation, the reversible addition of methyl groups at CpG dinucleotides, represents
an important regulatory layer associated with gene expression. Changed methylation status …

BACKGROUND: Stroke is among the leading causes of acquired disability in the United
States, affecting nearly 800,000 Americans annually. The identification of more effective …

Immune-checkpoint blockade has revolutionized cancer therapy. In particular, inhibition of
programmed cell death protein 1 (PD-1) has been found to be effective for the treatment of …

T cell immunity is central for the control of viral infections. CoVac-1 is a peptide-based vaccine
candidate, composed of SARS-CoV-2 T cell epitopes derived from various viral proteins 1 …

Scholars continue to find that political participation, especially beyond voting, is in limited
supply in the United States. However, the rise of the Internet provides possibilities to mitigate …

We used the 10x Genomics Visium platform to define the spatial topography of gene expression
in the six-layered human dorsolateral prefrontal cortex. We identified extensive layer-…

High-dimensional mass and flow cytometry (HDCyto) experiments have become a method
of choice for high-throughput interrogation and characterization of cell populations. Here, we …

Recent technological developments in high‐dimensional flow cytometry and mass cytometry
(CyTOF) have made it possible to detect expression levels of dozens of protein markers in …

Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet
survival and function - Weber - 2009 - Journal of Biomedical Materials Research Part A - Wiley …