[HTML][HTML] Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
Free fatty acids (FFAs) are important substrates for mitochondrial oxidative metabolism and
ATP synthesis but also cause serious stress to various tissues, contributing to the …
ATP synthesis but also cause serious stress to various tissues, contributing to the …
Commercial‐scale biotherapeutics manufacturing facility for plant‐made pharmaceuticals
…, DC Wilkerson, KYI Wong, LH Ly… - Plant biotechnology …, 2015 - Wiley Online Library
Rapid, large‐scale manufacture of medical countermeasures can be uniquely met by the
plant‐made‐pharmaceutical platform technology. As a participant in the Defense Advanced …
plant‐made‐pharmaceutical platform technology. As a participant in the Defense Advanced …
Developmental windows of susceptibility for epigenetic inheritance through the male germline
L Ly, D Chan, JM Trasler - Seminars in cell & developmental biology, 2015 - Elsevier
Exposure of developing male germ cells to environmental insults has been linked to
adverse effects in the offspring. One mechanism by which germ cell defects may be passed …
adverse effects in the offspring. One mechanism by which germ cell defects may be passed …
Effectiveness of family integrated care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial
…, S Lee, G Caouette, D McMillan, L Ly… - The Lancet Child & …, 2018 - thelancet.com
Background Despite evidence suggesting that parent involvement was beneficial for infant
and parent outcomes, the Family Integrated Care (FICare) programme was one of the first …
and parent outcomes, the Family Integrated Care (FICare) programme was one of the first …
Total neoadjuvant therapy with FOLFIRINOX in combination with losartan followed by chemoradiotherapy for locally advanced pancreatic cancer: a phase 2 clinical …
…, JW Clark, W Jiang, BY Yeap, LC Drapek, L Ly… - JAMA …, 2019 - jamanetwork.com
Importance Patients with locally advanced pancreatic cancer have historically poor outcomes.
Evaluation of a total neoadjuvant approach is warranted. Objective To evaluate the margin…
Evaluation of a total neoadjuvant approach is warranted. Objective To evaluate the margin…
Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial
…, EE Van Seventer, BE Foreman, LE Matlack, L Ly… - Nature cancer, 2021 - nature.com
Overcoming intrinsic resistance to immune checkpoint blockade for microsatellite stable (MSS)
colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) remains …
colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) remains …
Power analysis of single-cell RNA-sequencing experiments
… For coverage-based data, relative abundances were quantified with Salmon 41 0.6.0, with
library type parameter --l IU and the optional flag --biasCorrect. The Salmon transcriptome …
library type parameter --l IU and the optional flag --biasCorrect. The Salmon transcriptome …
[PDF][PDF] Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells
… reads against this alignment as a reference (Figure 2L, Table S2). The data show a clear …
, a highly preserved splice donor site (Figures 2L and 2M). Using the information from the split …
, a highly preserved splice donor site (Figures 2L and 2M). Using the information from the split …
Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria
…, AS Nair, UN Liligeto, MJT Stubbington, LH Ly… - Science …, 2017 - science.org
Differentiation of naïve CD4 + T cells into functionally distinct T helper (T H ) subsets is
crucial for the orchestration of immune responses. Because of extensive heterogeneity and …
crucial for the orchestration of immune responses. Because of extensive heterogeneity and …
Serverless computing: An investigation of factors influencing microservice performance
…, S Ramesh, S Chinthalapati, L Ly… - … conference on cloud …, 2018 - ieeexplore.ieee.org
Serverless computing platforms provide function(s)-as-a-Service (FaaS) to end users while
promising reduced hosting costs, high availability, fault tolerance, and dynamic elasticity for …
promising reduced hosting costs, high availability, fault tolerance, and dynamic elasticity for …